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Sanford 26th & Sycamore Family Medicine

Sanford's Family Medicine clinics provide care for the whole family - from babies to grandparents. We get to know you and your family and treat a variety of illnesses and injuries as part of your medical home. From annual physicals, regular check-ups, baby wellness, vaccinations, school and athletic physicals our family medicine providers serve families and communities throughout the region with the latest in care.

Looking for a Same Day appointment?  Schedule an appointment through Same Day at Sanford by calling the clinic or (855) SAME-DAY.

Walk in without an appointment for unexpected medical moments such as fevers, flus, sprains and more.  Click here for information on all locations. 

Click here to access acute care hours at this location.

Special Flu Vaccine Clinics

Thursday, Oct 5: 4pm to 6pm
Monday, Oct 9: 8am to 5pm 
Wednesday, Oct 11: 4pm to 6pm 
Friday, Oct 20: 8am to 5pm 
Wednesday, Oct 25: 4pm to 6pm 
Friday, Nov 10: 8am to 5pm

Or walk in anytime.


4405 E 26th Street
Sioux Falls, SD 57103


(605) 328-9000





M-F: 7:30 AM-9:00 PM
Sa, Su: 8:00 AM-7:00 PM