COVID-19 Vaccines

Getting Your COVID-19 Vaccine

Everyone ages 5 and older is eligible to get vaccinated against COVID-19. The vaccine can protect you, your family and your community from COVID-19.

Patients with My Sanford Chart

Log in to My Sanford Chart. Select Visits in the header and then click the Schedule an appointment button. You will see an option to schedule a COVID-19 and flu vaccination.

If you’re scheduling for a minor, you must have proxy access to their account. Learn more.

If you don’t have a My Sanford Chart account

If you’re 18 years old or older, schedule your appointment here.

For patients under 18, schedule an appointment here.

Walk-in COVID-19 Vaccine Locations

COVID-19 vaccines are offered without an appointment at select locations. We strongly encourage you to schedule your vaccination through My Sanford Chart or by calling (877) 701-0779

Find a COVID-19 vaccine event.


Are COVID-19 Boosters Available?

Sanford Health offers COVID-19 booster shots to everyone ages 18 and older. The Pfizer vaccine is available as a booster to those ages 16 and older.

Everyone who's eligible should get a booster vaccine, especially those in these categories:

  • People 50-years-old or older
  • Residents in long-term care facilities

Anyone 18 years old and older who received the Janssen (Johnson & Johnson) vaccine is eligible for a booster.

Schedule your booster shot at least six months after your second dose of the Pfizer or Moderna vaccine or two months after the Janssen (Johnson & Johnson) vaccine. You can receive any vaccine as a booster, no matter what you received for your initial dose(s).

Most Sanford Health locations carry the Pfizer vaccine. Call (877) 701-0779 to check if the Moderna or Janssen (Johnson & Johnson) vaccine is available at a location near you and to schedule an appointment.

Immunocompromised people should receive a third dose of the vaccine to get full protection. They are also eligible for a booster dose at least six months after their third dose.

Vaccines for Children Ages 5 to 11

Sanford Health is now offering the COVID-19 vaccine to children ages 5 to 11. Pfizer is the only manufacturer whose vaccine is approved for this age group.

Kids receive the same vaccine as adults but in a smaller dose. Their vaccine is a third of the adult dose.

They need two vaccinations given 21 days apart.

Contact Us

If you have questions about scheduling a vaccination appointment, call (877) 701-0779.

We’re available Monday through Friday from 8 a.m. to 5 p.m. If you’re hesitant about getting vaccinated, talk to an expert. My Sanford Nurse is available 24/7. Call your local line to speak to a Sanford Health registered nurse:

Sioux Falls region
(800) 445-5788 or (605) 333-4444
Please press 1

Fargo, Bismarck and Bemidji regions
(800) 821-5167 or (701) 234-5000
Please press 2

Getting Your COVID-19 Vaccine

Do I need a third vaccine dose?

Sanford Health offers a third dose of the Pfizer and Moderna COVID-19 vaccines to qualifying individuals. If you have a weakened immune system from ongoing cancer treatment, immunosuppressive medications or a health condition, you may be eligible.

To schedule a third dose of the Pfizer or Moderna vaccines, call (877) 701-0779.

Patients who received the Janssen (Johnson & Johnson) vaccine are not advised to get an additional dose at this time.

Who qualifies to receive a third dose?

A third dose of the Pfizer or Moderna COVID-19 vaccines is recommended for certain patients. People at a higher risk of serious complications from COVID-19 due to moderate or severe immune system problems should get a third dose.


  • Taking immune-suppressing or biologic drugs
  • Ongoing cancer treatment
  • Had an organ transplant
  • Had a stem cell transplant in the last two years
  • Primary immune deficiency diseases such as DiGeorge syndrome or Wiskott-Aldrich syndrome
  • Advanced or untreated HIV
  • High-dose steroid use (more than 20 milligrams of prednisone, 3 mg of dexamethasone or 80 mg of hydrocortisone each day)

You should receive the same mRNA vaccine (Pfizer or Moderna) as your previous doses for your third dose. It is acceptable to receive the other mRNA vaccine if it’s the only one available. You can receive your third dose anytime as long as it is at least 28 days after your second dose.

It’s not recommended for patients who received the Janssen (Johnson & Johnson) vaccine to get an additional dose at this time.

What’s the difference between a third dose of the COVID-19 vaccine and a vaccine booster?

A third dose is given to someone who had a weak immune response to their initial doses. This is seen most commonly in immunocompromised patients.

A booster is given to someone who had a proper immune response to a vaccine, but that response decreased over time. A booster for the COVID-19 vaccine (given eight months after the second dose) is not advised at this time. It may become available this fall after careful study by the FDA and CDC. These agencies are still collecting data and more guidance will be available in the future.

When and where can I receive a third dose?

Sanford Health is now offering third doses of the Pfizer and Moderna vaccines to qualifying patients. You can receive a third dose anytime as long as it is 28 days after your second dose.

Schedule your vaccination appointment by calling (877) 701-0779 or online through My Sanford Chart.

Please bring your vaccination card to your appointment.

What do I do if I lost my vaccination card or need a replacement of my record?

If you received your vaccination at Sanford Health, you have these options:

Option 1: Print your vaccination record from My Sanford Chart.

  1. Log in.
  2. In the menu, select Health Summary under My Record.
  3. Select the Immunizations tab and click View Details under your COVID-19 vaccine listing.
  4. This will display all doses of the COVID-19 vaccine you have on file. Click the printer icon in the upper right corner to print a paper copy or select Print to PDF for an electronic copy.

Option 2: Print your record from your state’s Department of Health.

Option 3: Contact your region’s Sanford Health Release of Information:

Option 4: Call your primary care provider and ask them to provide your vaccination record.

If you received your vaccination at a non-Sanford Health location, you can contact the site or clinic where you received your vaccination or print your record from your state’s Department of Health.

How can I update my medical records to include my COVID-19 vaccination?

To add your COVID-19 vaccination to your medical records, please call your primary care provider.

Can I make my own vaccine appointment or get one at my clinic?

Yes, you can schedule your vaccine appointment using our scheduling tool here. If you can’t schedule an appointment directly, you can register to get notified when a dose is available through Sanford Health’s vaccine registration form. Register now.

How do I notify my provider that I’ve been vaccinated?

If you’re a Sanford Health patient and receive the vaccine through us, that information will be automatically updated in your record.

If you received your COVID-19 vaccine at a non-Sanford Health location, please send a My Sanford Chart message to your provider and attach a picture of your vaccination card. Or email us and include:

  • First and last name
  • Date of birth
  • A picture of your vaccination card

This will ensure your medical record is updated with your vaccination status, date of vaccination and the type of vaccine you received.

If you don’t have your vaccination card available, please send a My Sanford Chart message or email us and include the following information:

  • First and last name
  • Date of birth
  • The date(s) of your vaccination
  • Type of vaccine you received
  • The state and location where you received your vaccine
  • Please indicate if you received your vaccination at Indian Health Services or Veterans Affairs (VA)

What should I do to prepare for my appointment and what can I expect ?

Make sure you’re ready for your appointment. At your appointment, remember to cover your mouth and nose with a mask and stay at least 6 feet away from others. Learn more about protecting yourself from COVID-19 during visits to the doctor or a pharmacy.


After your vaccination, you’ll get a card that tells you which COVID-19 vaccine you received, the date you got it and where. You’ll also get a fact sheet that tells you more about the specific COVID-19 vaccine you got. Each COVID-19 vaccine has its own fact sheet to help you understand the risks and benefits of receiving the vaccine.

You’ll also be observed on-site for 15 minutes after you receive the vaccine. During this time, we’ll help you schedule your appointment for your second dose. We’ll also give you information about v-safe, a free smartphone-based tool that uses text messaging and web surveys to provide personalized health check-ins after you receive a COVID-19 vaccination. V-safe also reminds you to get your second dose if you need one. Learn more about v-safe.

Do I need to start over if I miss my appointment for the second dose of the Pfizer or Moderna vaccine?

You won’t need to start over. Instead, you’ll need to reschedule your appointment for the second dose as close as possible to the recommended timing of 21 days for the Pfizer-BioNTech vaccine and 28 days for the Moderna vaccine.

I just received a different vaccine. Do I have to wait to get my COVID-19 vaccine?

You don’t have to wait or space out your vaccinations. We can now give COVID-19 vaccines and other vaccines on the same day.

I’ve recovered from COVID-19. Do I need to get the vaccine?

A COVID-19 vaccination should be offered to you regardless of whether you already had COVID-19. You will not be required to have an antibody test before you are vaccinated.

However, anyone currently infected with COVID-19 should wait to get vaccinated until after their illness has resolved and after they have met the criteria to stop isolating. Find the criteria here.

If I’ve gotten COVID-19 antibody therapy, do I need to wait to get the vaccine?

Yes. If you’ve received COVID-19 antibody therapy in the last 90 days, you need to wait at least 90 days before getting the COVID-19 vaccine.

Do I need to wait to get a mammogram after getting vaccinated?

All vaccines can cause swollen lymph nodes as a side effect. Women who get a mammogram shortly after a vaccine can have swollen lymph nodes show up on their mammogram, which can trigger follow-up tests.

If you received a COVID-19 vaccine within four weeks of your scheduled mammogram, contact your Edith Sanford Breast Center to discuss your appointment options.

Some women may elect to delay their mammogram until after they receive their final COVID-19 vaccine dose. However, if you are concerned about swelling or lumps, you should contact your physician right away.

About the COVID-19 Vaccine

Why get vaccinated?

Vaccines help keep you healthy by reducing your chance of being infected by a serious or deadly virus. They use your body’s natural defense system (immune system) to help you safely develop immunity against a disease. Plus, vaccines protect you when you get vaccinated as well as others in your family and community by stopping the spread of diseases.

Learn more about why you should get COVID-19 vaccine.

What are the ingredients in the vaccine?

The Pfizer COVID-19 vaccine includes the following ingredients: mRNA, lipids ((4-hydroxybutyl)azanediyl)bis(hexane-6,1-diyl)bis(2-hexyldecanoate), 2 [(polyethylene glycol)-2000]-N,N-ditetradecylacetamide, 1,2-Distearoyl-sn-glycero-3-phosphocholine, and cholesterol), potassium chloride, monobasic potassium phosphate, sodium chloride, dibasic sodium phosphate dihydrate and sucrose.

The Moderna COVID-19 vaccine contains the following ingredients: mRNA, lipids (SM-102, polyethylene glycol [PEG] 2000 dimyristoyl glycerol [DMG], cholesterol, and 1,2-distearoyl-sn-glycero-3-phosphocholine [DSPC]), tromethamine, tromethamine hydrochloride, acetic acid, sodium acetate and sucrose.

The Janssen (Johnson & Johnson) COVID-19 vaccine includes the following ingredients: recombinant, replication-incompetent adenovirus type 26 expressing the SARS-CoV-2 spike protein, citric acid monohydrate, trisodium citrate dihydrate, ethanol, 2-hydroxypropyl-β-cyclodextrin (HBCD), polysorbate-80 and sodium chloride.

Will the COVID-19 vaccine change my DNA?

The Pfizer and Moderna COVID-19 vaccines are mRNA vaccines, which work by giving instructions (mRNA) to your immune cells. The vaccine tells the cells to make a harmless protein called a spike protein, which mimics the protein that is found on the surface of the COVID-19 virus. Your immune system then recognizes the protein doesn’t belong in your body and will make antibodies to get rid of it. Through this process, the mRNA vaccine teaches your body to fight off any future COVID-19 infections.

mRNA vaccines don’t affect or alter your DNA in any way. They also can’t give you the COVID-19 virus. Instead, the vaccines work with your body’s natural defense system to safely build up protection against the COVID-19 virus.

Learn More About mRNA Vaccines

The Janssen (Johnson & Johnson) COVID-19 vaccine is a viral vector vaccine. It uses a modified version of a different virus as a vector, or carrier, to deliver instructions to cells. These instructions tell your cells to make a spike protein similar to the protein found on the surface of the COVID-19 virus. Your immune system will then recognize these proteins and make antibodies against them. These antibodies will know to target the COVID-19 virus if you are exposed in the future.

Viral vector vaccines are safe because they can’t combine with a person’s DNA. It is also impossible for these vaccines to infect you with COVID-19.

Learn More About Viral Vector Vaccines

What should I know about the current COVID-19 vaccines?

There are three vaccines available, including vaccines from Pfizer, Moderna and Janssen (Johnson & Johnson). The Pfizer vaccine received full approval from the FDA on Aug. 23. Moderna and Janssen (Johnson & Johnson) vaccines have received Emergency Use Authorization (EUA) from the FDA.

Both the Pfizer and Moderna vaccines require two doses given a few weeks apart. The first dose of a vaccine jump-starts an immune response and fires up antibody production. This is the body’s first opportunity to recognize and defend against the virus, but it is possible to get COVID-19 between your first and second dose. The second dose helps the body produce even more antibodies and strengthens the immune response.

Pfizer vaccines are given 21 days apart, and Moderna shots are given 28 days apart.

The Janssen (Johnson & Johnson) vaccine requires a single dose.

On Aug. 12, the FDA modified the EUA for Pfizer and Moderna to allow a third dose for immunocompromised people.

Do I have to pay for my COVID-19 vaccination?

At this time, there is no out-of-pocket cost for the vaccine. Private insurance companies and government insurance programs like Medicare will fully cover the cost.

How long will I have protection from COVID-19 after I’m vaccinated?

At this time, we don’t know for sure how long vaccinated individuals will be protected from COVID-19.

COVID-19 Vaccine Safety and Effectiveness

How effective are the COVID-19 vaccines?

Research shows that the COVID-19 vaccines effectively protect you from getting sick with COVID-19 – including the version of the disease caused by the delta variant. If you’re vaccinated, you’re protected against contracting, getting seriously ill and dying from COVID-19. This protection extends to several versions of the disease, including those caused by the delta variant.

The vaccines offer the most protection starting 14 days after your second dose of an mRNA vaccine (Pfizer or Moderna) or a single dose of the Janssen (Johnson & Johnson) vaccine.

We don’t know how effective the vaccines are against new variants that may develop in the future.

Are the COVID-19 vaccines safe?

Safety is our top priority. COVID-19 vaccines continue to be very safe and effective in preventing illness, hospitalization and death.

Before any vaccine receives approval for widespread use, it must be supported by research data. All vaccines approved for emergency use have undergone rigorous testing as directed by the Food and Drug Administration (FDA) to ensure safety and effectiveness.

As of April 16, Sanford Health has administered more than 250,000 vaccines with a significant adverse reaction rate of only .01%. This means there have been very few negative reactions among those who have received the vaccine.

Can I get COVID-19 after receiving the vaccine?

Getting the vaccine helps protect you from getting sick or severely ill with COVID-19, but no vaccine is 100%.

For the best protection, get all of the recommended doses of the COVID-19 vaccine. There have been breakthrough cases of fully vaccinated people contracting COVID-19, but these cases are a small percentage of the overall vaccinated population.

It’s also possible to get sick with COVID-19 just before or after vaccination. It typically takes around two weeks to get full protection after getting vaccinated.

While experts learn more, it’s still important to wear your mask in public if you’re in an area of high transmission. Also, keep washing your hands often and social distancing.

Are the vaccines safe for people who are pregnant or breastfeeding?

The American College of Obstetricians and Gynecologists, the Society for Maternal-Fetal Medicine and the CDC recommends that all pregnant people get COVID-19 vaccines.

Pregnant people are at a higher risk of COVID-19 complications, including a higher risk of:

  • Early (preterm) birth
  • Needing intensive care and a ventilator
  • Serious illness and death

A COVID-19 vaccine will help prevent or decrease the harm of getting COVID-19. These vaccines cannot give you the illness.

People who are pregnant experience the same vaccine side effects as others, including fever. Tylenol can be used during pregnancy for a high fever according to the CDC.

If you’re currently breastfeeding, experts say there’s no reason to think that the vaccines affect the safety of your breast milk. There is also evidence that antibodies from the vaccines pass from your breast milk to your baby. This may help protect your baby from infection.

Learn more.

What should I know about the vaccines and the delta variant?

The COVID-19 vaccines protect you from getting sick with COVID-19 or its variants, including the delta variant. Getting vaccinated will prevent or decrease the severity of a delta variant infection.

If you do contract COVID-19 after getting vaccinated, you’ll likely have an asymptomatic or very mild case. You’re also less likely to be hospitalized or die from the COVID-19 virus and its variants.

Who shouldn’t get the vaccine?

These groups shouldn’t get the COVID-19 vaccine:

  • Children under the age of 5 (Pfizer) or 18 [Moderna and Janssen (Johnson & Johnson)] will not be given the vaccine at this time. Clinical trials to test the vaccine in children are ongoing.
  • People who have had an immediate allergic reaction of any severity to an mRNA COVID-19 vaccine or any of its components, including polyethylene glycol (PEG).
  • People who have had an immediate allergic reaction of any severity to polysorbate.
  • People who have had a severe allergic reaction (anaphylaxis) to the first dose of an mRNA COVID-19 vaccine should not receive additional doses of either of the mRNA COVID-19 vaccines.
  • People who have had a severe allergic reaction to any of the ingredients in the Janssen (Johnson & Johnson) vaccine.

Read more about the risks and considerations of the COVID-19 vaccine.

What are the long-term effects of the vaccine?

At this time, there is no data about potential long-term side effects. However, it is extremely rare for vaccines to have negative long-term side effects that appear beyond the FDA’s required two-month monitoring period. All trials go through the monitoring period before they can get EUA.

What are the side effects of the vaccine?

For some, the COVID-19 vaccine may cause mild side effects. This isn’t a bad thing. Side effects show the vaccine is working and your body is building an immune response. The most common side effects of the COVID-19 vaccine are injection site pain, soreness and swelling. These side effects will typically resolve after one or two days.