Early Detection of Type 1 Diabetes and Celiac Disease in Children

Sanford Health has made a strong commitment to studying, preventing and curing type 1 diabetes (T1D). The Sanford PLEDGE study is a large-scale screening of children for T1D and celiac disease.

Through PLEDGE, we hope to find better ways to identify which children may be at risk of developing these diseases. Early detection and ongoing monitoring means kids could start treatment early enough to prevent serious illness.

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Who can Join the PLEDGE Study?

Children who:

  • Are ages 0-5 or ages 9-16
  • Do not have T1D
  • Receive routine care at Sanford Health
  • Have a My Sanford Chart account

Children ages 6 to 17 who have a sibling with T1D or T1D antibodies may also join the study.


How PLEDGE Works

Enroll through My Sanford Chart
Give permission for your child to participate in the study and provide access to their medical records.

Visit your Sanford Clinic Lab
A small amount of blood is collected up to three times with other routine blood draws or any other time it is convenient for your family.

See Results in My Sanford Chart
If your child screens positive for T1D or Celiac antibodies, our study team will contact you and your child’s primary care provider to discuss options for monitoring or intervention.


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Patients enrolled in PLEDGE

Patients monitored for T1D antibodies

Patients referred to GI for positive celiac antibodies


Sanford PLEDGE Study is proudly supported by