Complete care under one roof

Sanford’s USD Medical Center in Sioux Falls, SD, provides the latest in innovative care for patients from across the entire Midwest. In addition to being the largest hospital in South Dakota, the medical center is a teaching hospital for the Sanford School of Medicine at the University of South Dakota.

Our highly skilled medical teams are renowned for their passion, leadership and dedication to their patients and their specialties. Our comprehensive care includes emergency air transport, neonatal and pediatric intensive care, transplant services, and specialty centers in children’s, heart, cancer, neuroscience, sports medicine and women’s health. 

With 545 beds, 4,000 employees and a Level II Trauma Emergency Care center we are here to meet you and your family’s health care needs.

Committed to healthier communities

Every day we deliver on our mission of dedication to the work of health and healing, and every day we seek new ways to achieve our vision of improving the human condition through exceptional care, innovation and discovery.

Our promise to patients and employees remains strong as ever: Deliver a flawless experience that inspires.