Sanford USD Medical Center

Sanford USD Medical Center

Sanford’s USD Medical Center in Sioux Falls provides leading care for patients from across the Midwest. As the largest hospital in South Dakota, and a teaching hospital for the Sanford School of Medicine at the University of South Dakota, we are proud to offer the latest in innovative care. Our highly skilled medical teams are renown for their passion, leadership and dedication to their patients and their specialties.

We have been consistently named a Top 100 Hospital in the nation. Our comprehensive care includes emergency air transport, neonatal and pediatric intensive care, transplant services, and specialty centers in children’s, heart, cancer, neuroscience, sports medicine and women’s health. With 545 beds, 4,000 employees and a Level II Trauma Emergency Care center we are here to meet you and your family’s healthcare needs.

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My Sanford Nurse



1305 W 18th Street
Sioux Falls, SD 57117-5039


(605) 333-1000


M–Su: 12:00 AM–12:00 PM


Neonatal Intensive Care Unit

Sanford Children’s Neonatal Intensive Care Units (NICUs) offer unique, advanced healing environments designed to provide critically ill or premature babies with the latest in medical, physical and emotional care.

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