Study ID: COG ACCL0934

A Randomized Trial of Levofloxacin to Prevent Bacteremia in Children Being Treated for Acute Leukemia (AL) or Undergoing Hematopoietic Stem Cell Transplantation (HSCT)


The overall goal of this study is to compare the effects, good and/or bad, of levofloxacin on people receiving intensive cancer treatment or stem cell transplant to find out if it is better than no preventive bacterial infection treatment. Participants in this study will be receiving treatment for acute leukemia or a stem cell transplant. When patients receive intensive cancer treatment or a stem cell transplant, bacterial infections can develop. This study looks at how well treatment with an antibiotic, called levofloxacin, can prevent bacterial infection from developing in children and young adults receiving intensive cancer treatment or a stem cell transplant. The levofloxacin treatment to prevent bacterial infection is experimental.

Sioux Falls Region
Principal Investigator:
Kayelyn Wagner, MD
ALL (Acute Lymphocytic Leukemia), AML (Acute Myelogenic Leukemia), CCL
Phase III


Active - Partially Closed to Accrual

For more information, call or email Bismarck Clinical Research at (701) 323-5760, Fargo and Bemidji Clinical Research at (701) 234-5890, or Sioux Falls Clinical Research at (605) 328-1368.

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