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About Sanford Health in Sioux Falls, SD

Complete care under one roof

Sanford’s USD Medical Center in Sioux Falls, SD, provides the latest in innovative care for patients from across the entire Midwest. In addition to being the largest hospital in South Dakota, the medical center is a teaching hospital for the Sanford School of Medicine at the University of South Dakota.

Our highly skilled medical teams are renowned for their passion, leadership and dedication to their patients and their specialties. Our comprehensive care includes emergency air transport, neonatal and pediatric intensive care, transplant services, and specialty centers in children’s, heart, cancer, neuroscience, sports medicine and women’s health. 

With 545 beds, 4,000 employees and a Level II Trauma Emergency Care center we are here to meet you and your family’s health care needs.

Committed to healthier communities

Every day we deliver on our mission of dedication to the work of health and healing, and every day we seek new ways to achieve our vision of improving the human condition through exceptional care, innovation and discovery.

Our promise to patients and employees remains strong as ever: Deliver a flawless experience that inspires.

Address

1305 W 18th Street
Sioux Falls, SD 57117-5039
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General Info

(605) 333-1000

MySanfordNurse

(605) 333-4444
(800) 445-5788

Same Day

(855) SAME-DAY
(855) 726-3329

Sanford One Call

(877) 945-5678

1301 W 18th Street
Sioux Falls, SD 57105
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Hours:

M–F:


Other Hours

(605) 328-6055

1305 W 18th Street
Sioux Falls, SD 57105
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Hours:

M–F:


Other Hours

(605) 333-2226

1305 W. 18th St. P.O. Box 5039
Sioux Falls, SD 57117
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(605) 312-3520

(605) 312-3501

1305 W 18th Street
1st Floor
Sioux Falls, SD 57115
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Hours:

M–F:


Other Hours

(605) 328-6149

1309 W 17th Street
Suite G01
Sioux Falls, SD 57104
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(605) 328-5244

(605) 328-2867

5019 S Western Avenue
Suite 200
Sioux Falls, SD 57108
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(605) 328-5244

(605) 328-2867

5019 S Western Avenue
Suite 200
Sioux Falls, SD 57108
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Hours:

M–Th:
F:
Sa:


Other Hours

(605) 328-7155

1900 S Minnesota Avenue
Sioux Falls, SD 57105
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Hours:

M–F:
Sa:


Other Hours

(605) 370-6322

1309 W 17th Street
Suite 101
Sioux Falls, SD 57104
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(605) 328-8040

4405 E 26th Street
Sioux Falls, SD 57103
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Hours:

M–F:
Sa, Su:


Other Hours

(605) 332-2883

(605) 328-9081

4405 E 26th Street
Sioux Falls, SD 57103
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Hours:

M–F:


Other Hours

(605) 328-9000

(605) 312-9004

4405 E 26th Street
Sioux Falls, SD 57103
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Hours:

Su:
M–Sa:


Other Hours

(605) 328-9000

2701 S Kiwanis Avenue
Sioux Falls, SD 57105
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Hours:

M–F:


Other Hours

(605) 328-9100

(605) 328-9101

2701 S Kiwanis Avenue
Sioux Falls, SD 57105
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Hours:

M–F:


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(605) 328-9100

7220 W 41st Street
Sioux Falls, SD 57106
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Hours:

M–F:
Sa, Su:


Other Hours

(605) 332-2883

(605) 328-9620

7220 W 41st Street
Sioux Falls, SD 57106
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Hours:

M–F:


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(605) 328-9600

(605) 328-9620

7220 W 41st Street
Sioux Falls, SD 57106
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Hours:

M–F:
Sa, Su:


Other Hours

(605) 328-9600

3401 W 49th Street
Sioux Falls, SD 57106
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Hours:

M–F:


Other Hours

(605) 328-1850

(605) 328-1855

3401 W 49th Street
Sioux Falls, SD 57106
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Hours:

M–F:


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(605) 328-1850

600 N Sycamore Avenue
Sioux Falls, SD 57110
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Hours:

M–F:


Other Hours

(605) 328-2999

(605) 328-2957