(Sioux Falls, SD) – Four research projects have been selected to receive funding from the Sanford Seed Grant Research Fund, established in 2011 to grow and evolve unfunded research ideas of Sanford clinicians.
The proposals were selected based on the criteria of purpose and priority, scientific integrity, potential for future funding and feasibility.
“The Sanford Seed Grant Research Fund creates innovations in patient care at Sanford by resourcing the exploration of new ideas,” said David Pearce, PhD, chief operating officer and vice president of Sanford Research. “These grants fuel our physician-scientist culture by providing Sanford clinicians with the start-up resources required for bringing their research to the forefront.”
The recipients include the following:
- Dubert Guerrero, MD, & Paul Carson, MD, Sanford Clinic (Fargo), “Evaluation of patients with persistent Methicillin-Resistant Staphylococcus aureus colonization.” This study is a quality improvement initiative with the main goal of establishing a practical yet safe algorithm to reduce patients requiring contact precautions for Methicillin-resistant Staphylococcus aureus (MRSA).
- Lindsay Hines, PhD, & Thomas Haldis, DO, Sanford Neuroscience Clinic and Sanford Heart (Fargo), “Cognitive functioning improves following TAVI: Cerebral perfusion trumps embolic injury.” The aim of this study is to determine if cognitive functioning, mood and ability to manage activities of daily living improves following transcatheter aortic valve implantation (TAVI). The study will also compare post-TAVI changes in cognitive functioning with subclinical embolic brain injury as determined by magnetic resonance imaging (MRI).
- Angela Myers, MD, Michael Kruer, MD, & Patricia Crotwell, PhD, Sanford Children’s Specialty Clinic/Cytogenetics Lab (Sioux Falls), “Mapping novel genes for undiagnosed pediatric neurological diseases.” Using the resources and expertise within the Sanford Genetics Laboratory, this study will map currently undiscovered gene mutations that lead to inherited neurological diseases of childhood in highly genetically informative families.
- Kirstin Williams, NP, & Keith Miskimins, PhD, Sanford/USD Medical Center/Sanford Research (Sioux Falls), “Pilot study using metformin to reduce cardiac toxicity in breast cancer patients.” The objective of this study is to determine if co-administration of the medications metformin and doxorubicin in breast cancer patients receiving adjuvant therapy will reduce the number of patients who develop a significant change in left ventricular ejection fraction (LVEF).
About Sanford Research/USD
Sanford Research/USD is a non-profit research organization formed between Sanford Health and the University of South Dakota. Sanford Health is an integrated health system headquartered in Fargo, ND and Sioux Falls, SD and represents the largest, rural, not-for-profit healthcare system in the nation with a presence in 111 communities, eight states and three countries. In 2007, a transformational gift of $400 million by Denny Sanford provided for an expansion of children’s and research initiatives, specifically finding a cure for type 1 diabetes, and has given Sanford Research significant momentum in its goal of becoming one of the premiere research institutions in the United States and the world. Most recently, a subsequent gift of $100 million by Mr. Sanford has paved the way to establish Edith Sanford Breast Cancer Research.
With a team of more than 200 researchers, Sanford Research comprises several research centers, including Children’s Health Research, Edith Sanford Breast Cancer, Cancer Biology, Cardiovascular Health, Center for Health Outcomes and Prevention, and the National Institute for Athletic Health and Performance (NIAHP).