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Inflammatory breast cancer is a rare, fast-growing type of breast cancer. It is often called IBC for short.
Unlike other breast cancers, this type of cancer may not cause a lump in the breast. So regular breast exams and mammograms often fail to catch it early. Because it grows so fast, it usually has spread by the time it is diagnosed.
In this type of cancer, the cancer cells often do not form lumps in the breast. Instead, the cancer cells block the lymph vessels that normally keep lymph fluid moving in the breast.
When the normal flow of lymph fluid is blocked, it can make the breast look swollen and red and feel warm, as if it were infected. The swelling may cause lots of tiny dimples in the skin. Sometimes it causes a lump that grows quickly, but you can have inflammatory breast cancer without having a lump in your breast.
Inflammatory breast cancer can cause one or more of these symptoms:
A biopsy is needed to diagnose this cancer. During a biopsy, the doctor takes a sample of the breast or the breast skin. The sample is looked at in a lab to see if it contains cancer cells.
It's very important to diagnose inflammatory breast cancer quickly so that treatment can begin. But because it is rare and usually doesn't make a lump, doctors may not recognize the symptoms right away. The cancer is often mistaken for other problems, like spider bites, an allergic reaction, or mastitis, which is a breast infection that is usually treated with antibiotics.
Antibiotics do not help inflammatory breast cancer. If your doctor has given you antibiotics and your symptoms do not seem to be getting better after a week, call your doctor.
It's very important to treat this cancer as soon as possible. And more than one type of treatment may be needed. Treatment starts with anticancer drugs, called chemotherapy. These drugs help shrink the cancer.
Some tests will be done to help find which medicines will work best for you. These tests look at cancer cells from your biopsy to find out what kind of cancer you have. These tests include:
More chemotherapy or hormone therapy (or both) may be used after radiation, especially if cancer has spread to the lymph nodes.
Women who test positive for HER-2 may be treated with trastuzumab (Herceptin) during chemotherapy and afterwards.
Talk with your doctor about taking part in a clinical trial. Many women who have inflammatory breast cancer are good candidates for clinical trials, which study new treatments for IBC and better ways to use current treatments.
Inflammatory breast cancer is a very serious disease. But there is reason for hope, because treatment is improving. These days, many women are still free of cancer, some even 15 years and longer.
Talking with others who have breast cancer can help. To find a support group, contact your local branch of the American Cancer Society.
You may want to talk with your doctor about whether you are a good candidate for genetic testing for breast cancer. This can help other members of your family to understand more about their risk of breast cancer.
Additional information about inflammatory breast cancer is provided by the National Cancer Institute at www.cancer.gov/cancertopics/factsheet/Sites-Types/IBC.
|American Cancer Society (ACS)|
The American Cancer Society (ACS) conducts educational programs and offers many services to people with cancer and to their families. Staff at the toll-free number have information about services and activities in local areas and can provide referrals to local ACS divisions.
|7 East Lancaster Avenue, 3rd Floor|
|Ardmore, PA 19003|
Breastcancer.org is a website dedicated to helping women understand breast cancer and make good decisions about their treatment. This site provides information from medical professionals on all aspects of breast cancer, from screening and surgery to sex and intimacy. The site also offers links to chat rooms, discussion boards, and "Ask the Expert" online conferences.
|National Cancer Institute (NCI)|
|6116 Executive Boulevard|
|Bethesda, MD 20892-8322|
|Web Address:||www.cancer.gov (or https://livehelp.cancer.gov/app/chat/chat_launch for live help online)|
The National Cancer Institute (NCI) is a U.S. government agency that provides up-to-date information about the prevention, detection, and treatment of cancer. NCI also offers supportive care to people who have cancer and to their families. NCI information is also available to doctors, nurses, and other health professionals. NCI provides the latest information about clinical trials. The Cancer Information Service, a service of NCI, has trained staff members available to answer questions and send free publications. Spanish-speaking staff members are also available.
|National Lymphedema Network (NLN)|
|116 New Montgomery Street|
|San Francisco, CA 94105|
|Phone:||1-800-541-3259 (hotline) or (415) 908-3681|
The National Lymphedema Network (NLN) provides education and guidance to people with lymphedema and to health professionals and the general public. The NLN provides information on the prevention and management of primary and secondary lymphedema and supports research to find causes and treatments for lymphedema.
Other Works Consulted
- Burstein HJ, et al. (2011). Malignant tumors of the breast. In VT DeVita Jr et al., eds., DeVita, Hellman and Rosenberg's Cancer: Principles and Practice of Oncology, 9th ed., vol. 3, pp. 1401–1446. Philadelphia: Lippincott Williams and Wilkins.
- Merajver SD, et al. (2010). Inflammatory breast cancer. In JR Harris et al., eds., Diseases of the Breast, 4th ed., pp. 762–773. Philadelphia: Lippincott Williams and Wilkins.
- National Cancer Institute (2012). Breast Cancer Treatment PDQ—Health Professional Version. Available online: http://www.cancer.gov/cancertopics/pdq/treatment/breast/HealthProfessional.
- National Cancer Institute (2012). Inflammatory breast cancer. National Cancer Institute Fact Sheet. Available online: http://www.cancer.gov/cancertopics/factsheet/Sites-Types/IBC.
|Primary Medical Reviewer||Sarah Marshall, MD - Family Medicine|
|Specialist Medical Reviewer||Kirtly Jones, MD - Obstetrics and Gynecology|
|Last Revised||April 24, 2013|
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