Treatment for endometrial cancer depends on the size, stage, and grade of the cancer.
Endometrial cancer has been classified by the American Joint Committee on Cancer (AJCC) and the Fédération Internationale de Gynécologie et d’Obstétrique (FIGO, also called the International Federation of Gynecology and Obstetrics). The two classification systems are very similar.1
The primary tumor (T) is staged in the following way with the AJCC classification first and the FIGO stage in parentheses:
After the tumor (T) is staged, the TNM system stages lymph node involvement (N) to help determine the treatment options at each stage. Lymph node involvement is staged in the following way:
The last part of staging endometrial cancer is to find out whether cancer has spread to other areas of the body (metastasized). The TNM system stages metastasis (M) in the following way:
The TNM staging system allows your doctor to recommend the most effective treatment options and discuss the long-term outcome (prognosis) based on the type of tumor, the stage of your cancer, your age and overall health condition.
The FIGO stages and the AJCC TNM class are grouped in the following table.
|FIGO stage||TNM class|
Tis, N0, M0
T1, N0, M0
T1a, N0, M0
T1b, N0, M0
T2, N0, M0
T3, N0, M0
T3a, N0, M0
T3b, N0, M0
T1-T3, N1, M0
T1-T3, N2, M0
T4, any N, M0
Any T, any N, M1
The grade of endometrial cancer refers to how the cancer cells look under a microscope. Knowing the grade can help your doctor decide which treatment options are best for you. Endometrial cancer cells are described as well-differentiated, moderately differentiated, or poorly differentiated. Differentiation is a term used to describe how clearly the cancer cells can be distinguished from the surrounding normal tissues and how normal or abnormal the cells look.
Last Revised: November 29, 2010
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