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A nerve block relieves pain by interrupting how pain signals are sent to your brain. It is done by injecting a substance, such as alcohol or phenol, into or around a nerve or into the spine.
Nerve blocks may be used for several purposes, such as:
Nerve blocks are used to treat chronic pain when drugs or other treatments do not control pain or cause bad side effects. A test block is usually performed with local anesthetic. If you achieve good pain relief from the local anesthetic, your doctor may inject a nerve block, such as alcohol or phenol.
Nerve blocks numb the nerves touched by the drugs. This relieves pain by interrupting the pain signal sent by the nerves to your brain. Depending on the type of nerve block, your pain may be numbed for a short time or a long time.
Nerve blocks for chronic pain may work for 6 to 12 months. They may have to be repeated.
Nerve blocks are used to diagnose the causes of pain. They also are used to treat chronic pain when drugs or other treatments cause bad side effects or do not control pain.
Nerve blocks often relieve pain. Nerve blocks work well for some types of cancer pain, such as pain from cancer in organs such as the pancreas.1
Nerve blocks can cause serious complications, including paralysis and damage to the arteries that supply blood to the spinal cord. Other possible side effects include severely low blood pressure (hypotension), accidental injection of the alcohol or phenol into an artery, puncture of the lung, damage to the kidneys, diarrhea, and weakness in the legs.
Nerve blocks are not recommended if you have a disease that affects blood clotting, are taking blood-thinning drugs (such as heparin or warfarin), have a bowel obstruction, or have any type of uncontrolled infection.
Doctors can deaden a nerve with a probe that generates intense heat (radiofrequency denervation or ablation) or intense cold (cryoanalgesia).
A nerve block may cause temporary muscle paralysis or a loss of all feeling in the affected area or in the surrounding area.
Although nerve blocks can improve pain control, they do not help people to live longer.2
- National Comprehensive Cancer Network (2013). Adult cancer pain. NCCN Clinical Practice Guidelines in Oncology, version 1.2013. Available online: http://www.nccn.org/professionals/physician_gls/pdf/pain.pdf.
- Wong GY, et al. (2004). Effect of neurolytic celiac plexus block on pain relief, quality of life, and survival in patients with unresectable pancreatic cancer. JAMA, 291(9): 1092–1099.
Last Revised: October 31, 2011
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