Peyronie's disease is an abnormal curvature of the penis caused by scar tissue in the erectile tissue. Because the scar tissue prevents straightening of the penis, the curvature is most obvious during an erection. The curvature may be so severe that it prevents penetration during intercourse.
Peyronie's disease occurs over a wide range of ages, with some men as young as 18.
Although the exact cause of Peyronie's disease is unknown, some experts believe the scarring is caused by injury to the penis (such as bending or hitting).
Peyronie's disease is not caused by cancer and does not increase the risk of cancer. It is not caused by sexually transmitted diseases (STDs).
Symptoms of Peyronie's disease may develop slowly or suddenly. Common symptoms include:
Peyronie's disease is usually divided into two stages:
Peyronie's disease is usually diagnosed using a medical history and physical examination. Your doctor will ask you questions about when you first noticed your symptoms and whether the symptoms were gradual or sudden. This will help determine which stage of Peyronie's disease you are experiencing.
Because symptoms of Peyronie's disease are usually most noticeable when the penis is erect, your doctor may ask you to take a photograph of your penis while it is erect. Other tests that may be ordered include:
Treatment usually is not necessary unless Peyronie's disease causes pain or interferes with sexual function. Peyronie's disease goes away without treatment in some cases.
Most men are able to remain sexually active. Counseling can help couples maintain an active sexual life.
Although there is no standard treatment for Peyronie's disease, medicines (such as verapamil, potassium aminobenzoate, colchicine, or injected steroids) and vitamin E may help treat pain and improve sexual function. But the use of medicines has shown only limited success, and none are well studied for the treatment of Peyronie's disease.1
Surgery is considered for men who have severe pain, a severely curved penis, or sexual dysfunction related to Peyronie's disease. Surgical options include removing the scar tissue or shortening the unaffected side of the penis (plication). In some cases, use of a penile prosthesis may be used to help maintain an erection during intercourse.
|American Association of Sexuality Educators, Counselors, and Therapists (AASECT)|
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The National Kidney and Urologic Diseases Information Clearinghouse (NKUDIC), a federal agency, is a service of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK). NIDDK is part of the National Institutes of Health under the U.S. Department of Health and Human Services. The clearinghouse provides information about diseases of the kidneys and urologic system to people with kidney and urologic disorders and to their families, to health professionals, and to the public. NKUDIC answers inquiries; develops, reviews, and distributes publications; and works closely with professional and patient groups and government agencies to coordinate resources about kidney and urologic diseases.
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UrologyHealth.org is a website written by urologists for patients. Visitors can find specific topics by using the "search" option.
The website provides information about adult and pediatric urologic topics, including kidney, bladder, and prostate conditions. You can find a urologist, sign up for a free quarterly newsletter, or click on the Urology Resource Center to find materials about urologic problems.
- Jordan GH (2007). Peyronie's disease. In AJ Wein, ed., Campbell-Walsh Urology, 9th ed., vol. 1., pp. 818–838. Philadelphia: Saunders Elsevier.
Other Works Consulted
- Greenfield JM, Levine LA (2005). Peyronie's disease: Etiology, epidemiology and medical treatment. Urologic Clinics of North America, 32: 469–478.
- McAninch JW (2008). Disorders of the penis and male urethra. In EA Tanagho, JW McAninch, eds., Smith's General Urology, 17th ed., pp. 625–636. New York: McGraw-Hill Medical.
|Primary Medical Reviewer||E. Gregory Thompson, MD - Internal Medicine|
|Specialist Medical Reviewer||Christopher G. Wood, MD, FACS - Urology, Oncology|
|Last Revised||September 3, 2010|
Last Revised: September 3, 2010
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