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Restless Legs syndrome

National Organization for Rare Disorders, Inc.

Important
It is possible that the main title of the report Restless Legs syndrome is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • Willis-Ekbom disease

Disorder Subdivisions

  • None

General Discussion

Restless legs syndrome (RLS) is a neurologic and sleep related movement disorder characterized by an irresistible urge to move in the legs that typically occurs or worsens at rest. It is usually accompanied by abnormal, uncomfortable sensations, known as paresthesias or dysesthesias, that are often likened to crawling, cramping, aching, burning, itching, or prickling deep within the affected areas. Although the legs are usually involved, an urge to move with paresthesias or dysesthesias may also sometimes affect the arms or other areas of the body. Those with RLS may vigorously move the affected area, engage in pacing, or perform other, often repetitive movements, such as stretching, bending, or rocking. Symptoms typically worsen in the evening or at night, often resulting in sleep disturbances. Some individuals with RLS may also develop symptoms during other extended periods of inactivity, such as while sitting in a movie theater or traveling in a car.

RLS may occur as a primary condition or due to another underlying disorder, certain medications, or other factors (secondary or symptomatic RLS). In primary RLS, the disorder is often genetic in origin or occurs for unknown reasons (idiopathic). Secondary RLS may occur in association with certain conditions, such as iron deficiency, low levels of the oxygen-carrying component of red blood cells (anemia), kidney failure, or pregnancy.

Resources

WE MOVE (Worldwide Education and Awareness for Movement Disorders)
5731 Mosholu Avenue
Bronx, NY 10471
USA
Tel: (347)843-6132
Fax: (718)601-5112
Email: wemove@wemove.org
Internet: http://www.wemove.org

Restless Legs Syndrome Foundation, Inc.
1530 Greenview Dr SW
Suite 210
Rochester, MN 55902
Tel: (507)287-6465
Fax: (507)287-6312
Tel: (877)463-6757
Email: rlsfoundation@rls.org
Internet: http://www.rls.org

March of Dimes Birth Defects Foundation
1275 Mamaroneck Avenue
White Plains, NY 10605
Tel: (914)997-4488
Fax: (914)997-4763
Tel: (888)663-4637
Email: Askus@marchofdimes.com
Internet: http://www.marchofdimes.com

National Sleep Foundation
1010 N. Glebe Road
Suite 310
Arlington, VA 22201
Tel: (703)243-1697
Email: nsf@sleepfoundation.org
Internet: http://www.sleepfoundation.org

NIH/National Institute of Neurological Disorders and Stroke
P.O. Box 5801
Bethesda, MD 20824
Tel: (301)496-5751
Fax: (301)402-2186
Tel: (800)352-9424
TDD: (301)468-5981
Internet: http://www.ninds.nih.gov/

Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311
TDD: (888)205-3223
Internet: http://rarediseases.info.nih.gov/GARD/

Movement Disorder Society
555 E. Wells Street
Suite 1100
Milwaukee, WI 53202-3823
Tel: (414)276-2145
Fax: (414)276-3349
Email: info@movementdisorders.org
Internet: http://www.movementdisorders.org

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  3/13/2012
Copyright  1986, 1987, 1988, 1990, 1991, 1995, 1996, 1997, 1998, 1999, 2002, 2004, 2005, 2008, 2012 National Organization for Rare Disorders, Inc.

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