It is possible that the main title of the report Amyloidosis is not the name you expected.
Amyloidosis is a systemic disorder that is classified into several types. The different types of systemic amyloidosis are sometimes classified as primary, secondary or familial (hereditary). Primary amyloidosis (also called AL) is the most common type of systemic amyloidosis. AL results from an abnormality (dyscrasia) of plasma cells in the bone marrow and is closely related to multiple myeloma. Secondary (AA) amyloidosis is derived from the inflammatory protein serum amyloid A. AA occurs in association with chronic inflammatory disease such as the rheumatic diseases, familial Mediterranean fever, chronic inflammatory bowel disease, tuberculosis or empyema. Familial amyloidosis is a rare type of amyloidosis that is caused by an abnormal gene. There are several abnormal genes that can cause hereditary amyloidosis, but the most common type of hereditary amyloidosis is called ATTR and caused by mutations in the transthyretin (TTR) gene. Senile amyloidosis, in which the amyloid is derived from wild-type (normal) transthyretin, is a slowly progressive disease that affects the hearts of elderly men. Amyloid deposits may occasionally occur in isolation without evidence of a systemic disease; isolated bladder or tracheal amyloid are the most common such presentations.
International Myeloma Foundation
12650 Riverside Drive
North Hollywood, CA 91607
Multiple Myeloma Research Foundation
383 Main Avenue
Norwalk, CT 06851
Genetic and Rare Diseases (GARD) Information Center
PO Box 8126
Gaithersburg, MD 20898-8126
Amyloidosis Support Groups
232 Orchard Drive
Wood Dale, IL 60191
7151 N. Main Street
Clarkston, MI 48346
Who is Amy?
3856 Winona Ct.
Denver, CO 80212
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Last Updated: 10/25/2010
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