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Pronunciation: A doe tras TOOZ ue mab em TAN seen
Do not use ado-trastuzumab emtansine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
Ado-trastuzumab emtansine can harm your liver. Call your doctor at once if you have upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes).
Before you receive each ado-trastuzumab emtansine injection, your heart function may need to be checked using an electrocardiograph or ECG (sometimes called an EKG).
Ado-trastuzumab emtansine is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Ado-trastuzumab emtansine is used to treat a certain type of breast cancer that has spread to other parts of the body.
Ado-trastuzumab emtansine is usually given after other cancer medications have been tried without success.
Ado-trastuzumab emtansine may also be used for purposes not listed in this medication guide.
You should not use ado-trastuzumab emtansine if you are allergic to it, or if you are pregnant.
To make sure ado-trastuzumab emtansine is safe for you, tell your doctor if you have:
FDA pregnancy category D. Do not use ado-trastuzumab emtansine if you are pregnant. It could harm the unborn baby. Tell your doctor if you become pregnant during treatment. Use effective birth control while you are using this medication and for at least 6 months after your treatment ends.
You may need to have a negative pregnancy test before starting this treatment.
It is not known whether ado-trastuzumab emtansine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Before you receive this medicine, your doctor will perform blood tests to make sure ado-trastuzumab emtansine is the right medication to treat your cancer.
Ado-trastuzumab emtansine is injected into a vein through an IV. A healthcare provider will give you this injection.
Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when ado-trastuzumab emtansine is injected.
Ado-trastuzumab emtansine is usually given once every 3 weeks until your body no longer responds to the medication. Your doctor will determine how long to treat you with ado-trastuzumab emtansine.
You may need frequent medical tests at your doctor's office to be sure this medication is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests.
Call your doctor for instructions if you miss an appointment for your ado-trastuzumab emtansine injection.
Since this medication is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Avoid coming into contact with your body fluids (including urine, feces, vomit, semen, vaginal fluid). This medicine can pass into body fluids. Patients or caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
Some side effects may occur during the injection. Tell your caregiver right away if you feel cold, light-headed, feverish or sweaty, or have chest tightness, rapid heartbeats, or trouble breathing.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with ado-trastuzumab emtansine, especially:
This list is not complete. Other drugs may interact with ado-trastuzumab emtansine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Your doctor or pharmacist can provide more information about ado-trastuzumab emtansine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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