If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: per AM pa nel
Some people taking perampanel have had serious psychotic effects, especially when starting the medication.
Call your doctor right away if you have any changes in mood or behavior changes, personality changes, thoughts about suicide, or thoughts about hurting others. Your family or other caregivers should also be alert to changes in your mood or symptoms.
Before you take perampanel, tell your doctor if you have liver or kidney disease, or a history of depression, mental illness, or addiction to drugs or alcohol.
Tell your doctor right away if you become pregnant while taking perampanel for seizures. Do not start or stop taking perampanel during pregnancy without your doctor's advice.
Do not stop using any other seizure medication suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.
Never share perampanel with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
Perampanel is an anticonvulsant used to treat seizures in adults and children who are at least 12 years old.
Perampanel may also be used for purposes not listed in this medication guide.
You should not use perampanel if you are allergic to it, or if you have severe liver disease.
To make sure perampanel is safe for you, tell your doctor if you have:
Some people taking perampanel have had serious psychotic effects such as anger, aggression, feeling hostile or irritable, and thoughts about hurting others. These effects may be more likely to occur when you first start taking perampanel. Your family or other caregivers should also be alert to changes in your mood or symptoms.
FDA pregnancy category C. Do not start or stop taking perampanel during pregnancy without your doctor's advice. Having a seizure during pregnancy could harm both mother and baby. Tell your doctor right away if you become pregnant while taking perampanel.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of perampanel on the baby.
Perampanel can make certain birth control pills less effective. Ask your doctor about using non hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy while taking perampanel.
It is not known whether perampanel passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
Accidental falls may occur more often in elderly patients who take perampanel. Use caution to avoid falling or accidental injury while taking this medicine.
Do not give this medication to anyone under 12 years old without medical advice.
Perampanel is usually taken at bedtime. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.
Your doctor may occasionally change your dose to make sure you get the best results.
Do not stop using any other seizure medications suddenly, even if you feel fine. Stopping suddenly may cause increased seizures. Follow your doctor's instructions about tapering your dose.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Perampanel may be a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Call your doctor for instructions if you miss your perampanel dose for more than one day.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of perampanel.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Stop using perampanel and call your doctor at once if you have a side effect such as:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Taking perampanel with other drugs that make you sleepy or slow your breathing can increase these effects. Ask your doctor before taking perampanel with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Tell your doctor about all medicines you use, and those you start or stop using during your treatment with perampanel, especially:
This list is not complete. Other drugs may interact with perampanel, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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