If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: kar FILZ oh mib
Carfilzomib can affect your heart or lungs. Call your doctor at once if you have chest pain, pounding heartbeats, shortness of breath (even with mild exertion or while lying down), swelling of your hands or feet, pounding heartbeats or fluttering in your chest, feeling like you might pass out, wheezing, gasping for breath, cough with foamy mucus, or blue colored appearance of your lips and skin.
Carfilzomib is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Carfilzomib is used to treat multiple myeloma.
Carfilzomib is usually given after at least two other cancer medications have been tried without success.
Carfilzomib may also be used for purposes not listed in this medication guide.
You should not use carfilzomib if you are allergic to it.
To make sure carfilzomib is safe for you, tell your doctor if you have:
FDA pregnancy category D. Do not use carfilzomib if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with carfilzomib. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
It is not known whether carfilzomib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Carfilzomib is injected into a vein through an IV. A healthcare provider will give you this injection.
Carfilzomib is given in a 28-day treatment cycle. You will receive an injection only on certain days of this cycle.
Your doctor will determine how many treatment cycles you should receive.
You may be given medication to prevent certain side effects while you are receiving carfilzomib. Drink plenty of liquids before and after your carfilzomib injections.
Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while receiving this medication.
You may need frequent medical tests to be sure this medication is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Avoid coming into contact with your body fluids (including urine, feces, vomit, semen, vaginal fluid). This medicine can pass into body fluids. Patients or caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
This medication may cause you to feel light-headed or short of breath. Be careful if you drive or do anything that requires you to be alert.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some side effects may occur within 24 hours after the injection. Tell your caregiver right away if you feel dizzy, weak, nauseated, light-headed, feverish, sweaty, or if you have joint or muscle pain, a headache, chest tightness, back pain, trouble breathing, or swelling in your face.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Other drugs may interact with carfilzomib, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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