What is azilsartan and chlorthalidone?
Azilsartan is an angiotensin II receptor antagonist. Azilsartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Chlorthalidone is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
The combination of azilsartan and chlorthalidone is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Azilsartan and chlorthalidone is sometimes given together with other blood pressure medications.
Azilsartan and chlorthalidone may also be used for purposes not listed in this medication guide.
How should I take azilsartan and chlorthalidone?
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Azilsartan and chlorthalidone may be taken with or without food.
Your blood pressure will need to be checked often. Visit your doctor regularly.
Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.
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Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. |
Azilsartan and chlorthalidone is only part of a complete program of treatment that may also include diet, exercise, weight control, smoking cessation, and other medications. Follow your doctor's instructions very closely. Changing any of these factors can affect your blood pressure.
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To be sure this medication is not causing harmful effects, your kidney function may need to be tested. Visit your doctor regularly. |
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Store in the original container at room temperature, away from moisture, heat, and light. |
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. |
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
What should I avoid while taking azilsartan and chlorthalidone?
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Drinking alcohol can further lower your blood pressure and may increase certain side effects of azilsartan and chlorthalidone. |
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Do not use potassium supplements or salt substitutes while you are taking azilsartan and chlorthalidone, unless your doctor has told you to. |
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Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall. |
What are the possible side effects of azilsartan and chlorthalidone?
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. |
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Call your doctor at once if you have a serious side effect such as: |
- feeling like you might pass out;
- urinating less than usual or not at all;
- drowsiness, confusion, mood changes, increased thirst, loss of appetite, vomiting;
- swelling, weight gain, feeling short of breath; or
- electrolyte imbalance (dry mouth, extreme thirst, drowsiness, restless feeling, confusion, nausea and vomiting, increased or decreased urination, constipation, muscle pain or weakness, fast heart rate, or seizure (convulsions)).
Less serious side effects may include:
- diarrhea, nausea, upset stomach;
- mild skin rash;
- cough;
- mild dizziness; or
- weakness, tired feeling.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect azilsartan and chlorthalidone?
Tell your doctor about all other medicines you use, especially:
- other blood pressure medications;
- digoxin (Lanoxin, Lanoxicaps);
- lithium (Lithobid);
- any other diuretic (water pill); or
- a non-steroidal anti-inflammatory drug (NSAID) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others.
This list is not complete and other drugs may interact with azilsartan and chlorthalidone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Where can I get more information?
Your pharmacist can provide more information about azilsartan and chlorthalidone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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