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|Pronunciation:||RIL pi VIR een|
|The following drugs should not be used while you are taking rilpivirine: carbamazepine (Carbatrol, Equetro, Tegretol, Teril, Epitol), oxcarbazepine (Trileptal), phenobarbital (Solfoton, Luminal), phenytoin (Dilantin, Phenytek), rifabutin (Mycobutin), rifampin (Rifater, Rifadin, Rifamate, Rimactane), rifapentine (Priftin), esomeprazole (Nexium, Vimovo), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), rabeprazole (Aciphex), St John's wort, delavirdine (Rescriptor), efavirenz (Sustiva, Atripla), etravirine (Intelence), nevirapine (Viramune), or more than one dose of dexamethasone (Cortastat, Dexasone, Solurex, DexPak).|
|Using any of these medicines while you are taking rilpivirine can cause serious medical problems or death.|
Many other medicines can interact with rilpivirine, or make it less effective. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Before you take rilpivirine, tell your doctor if you have liver disease (including hepatitis B or C), kidney disease, a history of depression or mental illness, or if you have ever taken any HIV medication in the past.
|Do not take rilpivirine as your only HIV medication. HIV/AIDS is usually treated with a combination of different drugs. Your disease may become resistant to rilpivirine if you do not take it in combination with other HIV medicines your doctor has prescribed.|
|Call your doctor at once if you have mood changes, anxiety, severe depression, feeling hopeless, or thoughts about suicide or hurting yourself.|
Taking this medication will not prevent you from passing HIV to other people.
Rilpivirine is an antiviral medication that prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Rilpivirine is used to treat HIV, which causes the acquired immunodeficiency syndrome (AIDS). Rilpivirine is not a cure for HIV or AIDS.
|Do not take rilpivirine as your only HIV medication. Rilpivirine must be used in combination with other HIV medicines that your doctor has prescribed.|
Rilpivirine may also be used for purposes not listed in this medication guide.
|You should not use rilpivirine if you are allergic to it.|
|Many other drugs can cause serious or life threatening medical problems if you take them together with rilpivirine. The following drugs should not be used while you are taking rilpivirine:|
To make sure you can safely take rilpivirine, tell your doctor if you have any of these other conditions:
FDA pregnancy category B. Rilpivirine is not expected to harm an unborn baby, but HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of rilpivirine on the baby.
|Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.|
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
|Rilpivirine is usually taken once per day with a meal. Always take the medicine with food.|
Use rilpivirine regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
|To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.|
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
|Store at room temperature away from moisture, heat, and light.|
If you are less than 12 hours late in taking your medicine, take the missed dose with food as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
|Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.|
If you also take an antacid, take it at least 2 hours before or 4 hours after taking rilpivirine. Do not take an antacid and rilpivirine at the same time.
If you also take didanosine (Videex), take it at least 2 hours before or 4 hours after taking rilpivirine.
If you also take a stomach acid reducer, take it at least 12 hours before or 4 hours after taking rilpivirine. This includes cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid), and ranitidine (Zantac). Do not take rilpivirine and this type of stomach medicine at the same time.
|Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.|
|Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.|
|Call your doctor at once if you have any of these serious side effects:|
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
|This list is not complete and there are many other medicines that can interact with rilpivirine, or make it less effective. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.|
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 1.03. Revision date: 10/18/2012.
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