|Pronunciation:||am LOE di peen, HYE droe KLOR oh THYE a zide, and OL me SAR tan|
|Do not take this medication if you are pregnant. Stop using the medication and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.|
|You should not use this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic), or olmesartan (Benicar), or if you have severe kidney disease, if you are unable to urinate, or if you are allergic to sulfa drugs.|
Before you take amlodipine, hydrochlorothiazide, and olmesartan, tell your doctor if you have kidney or liver disease, congestive heart failure, angina (chest pain), severe coronary artery disease, glaucoma, lupus, diabetes, a penicillin allergy, if you are dehydrated, or if you are vomiting or having diarrhea.
|You should not breast-feed while you are taking this medication.|
Call your doctor at once if you have any signs of an electrolyte imbalance, such as: headache, trouble concentrating, memory problems, weakness, feeling unsteady, nausea, loss of appetite, extreme thirst, increased urination, leg discomfort, jerking muscle movements, muscle weakness or limp feeling, shallow breathing, uneven heart rate, confusion, feeling tired or restless, hallucinations, fainting, or seizure.
Amlodipine is a calcium channel blocker. Amlodipine relaxes (widens) blood vessels and improves blood flow.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Olmesartan is an angiotensin II receptor antagonist. Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
The combination of amlodipine, hydrochlorothiazide, and olmesartan is used to treat high blood pressure (hypertension). This medication is usually given after others have been tried without successful treatment of hypertension.
Amlodipine, hydrochlorothiazide, and olmesartan may also be used for purposes not listed in this medication guide.
|You should not use this medication if you are allergic to amlodipine (Norvasc), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Vaseretic, Zestoretic), or olmesartan (Benicar), or if you have:|
To make sure you can safely take amlodipine, hydrochlorothiazide, and olmesartan, tell your doctor if you have any of these other conditions:
|FDA pregnancy category D. Do not take amlodipine, hydrochlorothiazide, and olmesartan if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking this medication.|
|It is not known whether amlodipine, hydrochlorothiazide, and olmesartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking this medication.|
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Your doctor may occasionally change your dose to make sure you get the best results.
Amlodipine, hydrochlorothiazide, and olmesartan is usually taken once per day. Follow your doctor's instructions.
This medication may be taken with or without food.
|You may have new or worsening chest pain when you first start taking amlodipine, hydrochlorothiazide, and olmesartan or when your dose is increased. Call your doctor if your chest pain is severe or ongoing.|
Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Conditions that may cause very low blood pressure include: vomiting, diarrhea, heavy sweating, heart disease, dialysis, a low-salt diet, or taking diuretics (water pills). Tell your doctor if you have a prolonged illness that causes diarrhea or vomiting.
Your blood pressure will need to be checked often. Visit your doctor regularly.
Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using a thiazide diuretic.
|Store at room temperature away from moisture and heat.|
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
|Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.|
Overdose symptoms may include extreme dizziness, fast or slow heartbeat, or fainting.
|Do not use potassium supplements or salt substitutes while you are taking amlodipine, hydrochlorothiazide, and olmesartan, unless your doctor has told you to.|
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
|Drinking alcohol can further lower your blood pressure and may increase certain side effects of this medication.|
|Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.|
|Call your doctor at once if you have any other serious side effects, such as:|
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medicines you use, especially:
This list is not complete and other drugs may interact with amlodipine, hydrochlorothiazide, and olmesartan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your pharmacist can provide more information about amlodipine, hydrochlorothiazide, and olmesartan.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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