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Pronunciation: OH ma se TAX een
Omacetaxine can lower blood cells that help your body fight infections and help your blood to clot. You may get an infection or bleed more easily. Call your doctor if you have unusual bruising or bleeding, or signs of infection (fever, chills, body aches).
Omacetaxine is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Omacetaxine is used to treat chronic myeloid leukemia (CML).
Omacetaxine is usually given after other cancer medications have been tried without success.
Omacetaxine may also be used for purposes not listed in this medication guide.
You should not use omacetaxine if you are allergic to it.
To make sure omacetaxine is safe for you, tell your doctor if you have:
FDA pregnancy category D. Do not use omacetaxine if you are pregnant. It could harm the unborn baby. Use effective birth control to avoid pregnancy during your treatment with omacetaxine. Follow your doctor's instructions about how long to prevent pregnancy after your treatment ends.
It is not known whether omacetaxine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
Omacetaxine is injected under the skin. A healthcare provider will give you this injection.
If this medicine accidentally gets on your skin, wash it thoroughly with soap and warm water.
Omacetaxine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.
Call your doctor for instructions if you miss an appointment for your omacetaxine injection.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Avoid coming into contact with your body fluids (including urine, feces, vomit, semen, vaginal fluid). This medicine can pass into body fluids. Patients or caregivers should wear rubber gloves while cleaning up body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
Body fluids should not be handled by a woman who is pregnant or who may become pregnant. Use condoms during sexual activity to avoid exposure to body fluids.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
Common side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Other drugs may interact with omacetaxine, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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