If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: FOS a PREP i tan t
Brand: Emend for Injection
You should not receive fosaprepitant if you are taking cisapride (Propulsid) or pimozide (Orap). These drugs may cause life-threatening interactions when taken together with fosaprepitant.
Before you receive fosaprepitant, tell your doctor if you have liver disease. You may need a dose adjustment or special tests to safely use this medication.
Fosaprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with fosaprepitant, and for 1 month afterward.
There are many other medicines that can interact with fosaprepitant. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Do not start using a new medication without telling your doctor. Keep a list with you of all the medicines you use and show this list to any doctor or other healthcare provider who treats you.
Fosaprepitant blocks the actions of chemicals in the body that trigger nausea and vomiting.
Fosaprepitant is used together with other medications to prevent nausea and vomiting that may be caused by cancer chemotherapy.
Fosaprepitant is given ahead of time and will not treat nausea or vomiting that you already have.
Fosaprepitant may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to fosaprepitant, aprepitant (oral Emend).
The following drugs should not be used while you are receiving fosaprepitant:
To make sure you can safely take fosaprepitant, tell your doctor if you have liver disease.
Fosaprepitant can make birth control pills less effective, resulting in pregnancy. This effect can last for up to 28 days after your last dose of this medication. Talk to your doctor about the use of a non-hormonal back-up form of birth control (such as condoms, a diaphragm, or spermicides) during treatment with fosaprepitant and for at least 1 month after your treatment ends.
FDA pregnancy category B. Fosaprepitant is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while you are being treated with fosaprepitant.
It is not known whether fosaprepitant passes into breast milk or if it could harm a nursing baby. Before you receive this medication, tell your doctor if you are breast-feeding a baby.
Fosaprepitant is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting. Fosaprepitant must be given slowly, and the IV infusion can take at least 15 minutes to complete.
The first dose of fosaprepitant is usually given 30 minutes before your chemotherapy treatment begins.
You may also be given other medicines, including oral Emend (aprepitant capsules), for 3 or 4 days to further help prevent nausea and vomiting.
Fosaprepitant is not for long-term use.
Since fosaprepitant injection is given only once on the first day of your chemotherapy treatment, you are not likely to be on a dosing schedule.
An overdose of this medication is not likely to occur since it is given by a healthcare professional. However, overdose symptoms may include drowsiness and headache.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are being treated with fosaprepitant.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have any of these serious side effects:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor if about all other medicines you use, especially:
This list is not complete and other drugs may interact with fosaprepitant. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your doctor or pharmacist can provide more information about fosaprepitant.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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