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|Pronunciation:||dye EN oh jest and ESS tra DYE ole|
|Smoking can increase your risk of blood clots, stroke, or heart attack caused by birth control pills, especially if you are older than 35.|
|This medication can harm an unborn baby or cause birth defects. Do not use dienogest and estradiol if you are pregnant.|
|Do not use this medication if you have a history of heart attack or stroke, a history of blood clot or coronary artery disease, circulation problems (especially if caused by diabetes), a blood clotting disorder, breast or uterine cancer, abnormal vaginal bleeding, eye problems or kidney problems caused by diabetes, liver disease or liver cancer, uncontrolled high blood pressure, severe migraine headaches, a heart valve or heart rhythm disorder, or if you smoke and you are over 35 years old.|
Some drugs can make birth control pills less effective, which may result in pregnancy. Tell your doctor about all medications you use.
Dienogest and estradiol is a combination of female hormones that prevent ovulation (the release of an egg from an ovary). This medication also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.
Dienogest and estradiol is used as contraception to prevent pregnancy.
Dienogest and estradiol may also be used for purposes not listed in this medication guide.
|This medication can harm an unborn baby or cause birth defects. Do not use if you are pregnant. Tell your doctor right away if you become pregnant, or if you miss two menstrual periods in a row. If you have recently had a baby, wait at least 4 weeks before taking birth control pills.|
|Do not use this medication if you are allergic to dienogest or estradiol, or if you have:|
To make sure you can safely take this medicine, tell your doctor if you have any of these other conditions:
|The hormones in this medication can pass into breast milk and may harm a nursing baby. This medication may also slow breast milk production. Do not use if you are breast feeding a baby.|
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Take your first pill on the first day of your period or on the first Sunday after your period begins. Follow the directions on your prescription label. The 28 day birth control pack contains five different colors of pills. Take one pill each day in the exact order directed on the blister pack.
Take one pill every day, no more than 24 hours apart. When the pills run out, start a new pack the following day. Get your prescription refilled before you run out of pills completely.
|You may need to use back up birth control, such as condoms or a spermicide, when you first start using this medication. Follow your doctor's instructions. Do not take two different kinds of birth control pills at the same time.|
If you are switching to this medication from another birth control pill, start taking dienogest and estradiol on the first day of your withdrawal bleeding and stop taking the other birth control pills. If you were taking progestin only pills before, start taking dienogest and estradiol on the day you would have taken your next pill.
If you are switching from a birth control implant, intrauterine device (IUD), vaginal ring, or skin patch, start taking dienogest and estradiol on the day the other birth control device is removed.
If you are switching from a birth control injection, start taking dienogest and estradiol on the day you would have received your next scheduled injection.
You may have breakthrough bleeding. Tell your doctor if this bleeding continues or is very heavy.
Use a back up birth control if you are sick with severe vomiting or diarrhea. Vomiting within 4 hours after your dose is the same as missing a pill.
|If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medication for a short time. Any doctor or surgeon who treats you should know that you are using birth control pills.|
|Store at room temperature away from moisture and heat.|
If you are less than 12 hours late in taking your pill, take the missed dose as soon as you remember. Take the next pill at the usual time, then take one pill per day in the order directed on the pack. Missing a pill by more than 12 hours increases your risk of becoming pregnant.
If you miss one pill:
If you miss two pills:
|Your risk of getting pregnant will increase with the number of pills you miss. If you miss a period for two months in a row, call your doctor because you might be pregnant. Use back-up birth control if you are not sure how many pills you have missed.|
|Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, or vaginal bleeding.|
|Do not smoke while using this medication, especially if you are older than 35. Smoking can increase your risk of blood clots, stroke, or heart attack caused by birth control pills.|
Birth control pills will not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to protect yourself from these diseases.
|Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.|
|Stop using this medication and call your doctor at once if you have a serious side effect such as:|
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Many drugs can make birth control pills less effective, which may result in pregnancy. Below is just a partial list:
This list is not complete and other drugs may interact with dienogest and estradiol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your pharmacist can provide more information about dienogest and estradiol.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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