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antihemophilic factor-von Willebrand factor complex

Pronunciation: an tee hee moe FIL ik FAK tor - von WIL e brand FAK tor

Brand: Alphanate, Humate-P

What is the most important information I should know about antihemophilic factor-von Willebrand factor complex?

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Do not use this medication if you have ever had a severe allergic reaction to antihemophilic factor in the past.

Before using antihemophilic factor-von Willebrand factor complex, tell your doctor if you have ever had a stroke or a blood clot.

Your body may develop antibodies to this medication, making it less effective. Call your doctor if this medicine seems to be less effective in controlling your bleeding.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.

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Wear a medical alert tag or carry an ID card stating that you have hemophilia or von Willebrand disease in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder.

Antihemophilic factor-von Willebrand factor complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

What is antihemophilic factor-von Willebrand factor complex?

Antihemophilic factor is a naturally occurring protein in the blood that helps blood to clot.

A lack of antihemophilic factor VIII is the cause of hemophilia A. A lack of an antihemophilic factor called von Willebrand factor is the cause of von Willebrand disease.

This medication works by temporarily raising levels of factor VIII or von Willebrand factor in the blood to aid in clotting.

Antihemophilic factor-von Willebrand factor complex is used to treat or prevent bleeding episodes in adults with hemophilia A. It is also used to treat injury-related bleeding episodes in adults and children with von Willebrand disease.

Antihemophilic factor-von Willebrand factor complex may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before using antihemophilic factor-von Willebrand factor complex?

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Do not use this medication if you have ever had a severe allergic reaction to antihemophilic factor in the past.

To make sure you can safely use this medication, tell your doctor if you have ever had a stroke or a blood clot.

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FDA pregnancy category C. It is not known whether antihemophilic factor-von Willebrand factor complex will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

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It is not known whether antihemophilic factor-von Willebrand factor complex passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Antihemophilic factor-von Willebrand factor complex is made from human plasma (part of the blood) which may contain viruses and other infectious agents. Donated plasma is tested and treated to reduce the risk of it containing infectious agents, but there is still a small possibility it could transmit disease. Talk with your doctor about the risks and benefits of using this medication.

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Your doctor may want you to receive a hepatitis vaccination before you start using antihemophilic factor-von Willebrand factor complex.

How should I use antihemophilic factor-von Willebrand factor complex?

Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Antihemophilic factor-von Willebrand factor complex is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.

This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.

Antihemophilic factor-von Willebrand factor complex is usually given every 8 to 12 hours for up to 7 days, depending on the reason you are using the medication.

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Always wash your hands before preparing and giving your injection.

Antihemophilic factor-von Willebrand factor complex must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medication.

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You may gently swirl the medicine and diluent to mix them, but do not shake the vial (bottle). Vigorous shaking can ruin the medicine.

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After mixing the medicine with a diluent, store at room temperature and use it within 3 hours. Do not refrigerate.

Prepare your dose in a syringe only when you are ready to give yourself an injection. Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.

Each single use vial (bottle) of this medicine is for one use only. Throw away after one use, even if there is still some medicine left in it after injecting your dose.

Use a disposable needle only once. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Your body may develop antibodies to antihemophilic factor, making it less effective. Call your doctor if this medicine seems to be less effective in controlling your bleeding.

To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Visit your doctor regularly.

Multum emt

Wear a medical alert tag or carry an ID card stating that you have hemophilia or von Willebrand disease in case of emergency. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder.

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Store the medication and diluent at room temperature, away from moisture and heat. Throw away any unused medicine after the expiration date on the label has passed.

What happens if I miss a dose?

Antihemophilic factor-von Willebrand factor complex is sometimes used only as needed, so you may not be on a dosing schedule. If you are using the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using antihemophilic factor-von Willebrand factor complex?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of antihemophilic factor-von Willebrand factor complex?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have a serious side effect such as:

  • easy bruising, increased bleeding episodes;
  • bleeding from a wound or where the medicine was injected;
  • low fever with skin rash, and joint pain, swelling, or stiffness;
  • sudden numbness or weakness, especially on one side of the body;
  • sudden severe headache, confusion, problems with vision, speech, or balance;
  • black, bloody, or tarry stools;
  • coughing up blood or vomit that looks like coffee grounds; or
  • nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Less serious side effects may include:

  • constipation;
  • swelling, stinging, or irritation where the injection was given;
  • skin rash or itching;
  • swelling in your hands or feet;
  • pain in your arms or legs;
  • chills; or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect antihemophilic factor-von Willebrand factor complex?

There may be other drugs that can interact with antihemophilic factor-von Willebrand factor complex. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about antihemophilic factor-von Willebrand factor complex.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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