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|Pronunciation:||tip RA na veer|
Do not use this medication if you are allergic to tipranavir or ritonavir (Norvir), or if you have moderate to severe liver disease.
|Life-threatening side effects can occur if you take tipranavir with any of the following medications: alfuzosin (Uroxatral), amiodarone (Cordarone, Pacerone), bepridil (Vascor), cisapride (Propulsid), flecainide (Tambocor), lovastatin (Mevacor, Altoprev, Advicor), sildenafil (Revatio for pulmonary arterial hypertension), simvastatin (Zocor, Simcor, Vytorin), propafenone (Rythmol), rifampin (Rifadin, Rifamate, Rimactane), quinidine (Quin-G), pimozide (Orap), midazolam (Versed), triazolam (Halcion), St. John's wort, or an ergot medicine such as Ergomar, Ergotrate, Cafergot, D.H.E. 45, Migranal, or Methergine.|
There are many other medicines that can interact with tipranavir. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors.
|Tipranavir is used in combination with a similar drug called ritonavir (Norvir). Some people taking this combination of medicines have developed life-threatening medical problems including liver damage and bleeding in the brain. If you are taking these two medications, call your doctor at once if you have any of the following side effects:|
Tipranavir is an antiviral medication in a group of HIV medicines called protease (PRO-tee-ayz) inhibitors. Tipranavir prevents human immunodeficiency virus (HIV) cells from multiplying in your body.
Tipranavir is used to treat HIV, which causes acquired immunodeficiency syndrome (AIDS). Tipranavir is not a cure for HIV or AIDS.
Tipranavir may also be used for purposes not listed in this medication guide.
|Do not use this medication if you are allergic to tipranavir or ritonavir (Norvir), if you have moderate to severe liver disease, or if you are using any of the following drugs:|
Life-threatening side effects can occur if you take tipranavir with any of the following medications:
If you have any of these other conditions, you may need a tipranavir dose adjustment or special tests:
|FDA pregnancy category C. It is not known whether tipranavir will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. HIV can be passed to your baby if you are not properly treated during pregnancy. Take all of your HIV medicines as directed to control your infection.|
|Tipranavir can make birth control pills less effective. Ask your doctor about using a non-hormone method of birth control (such as a condom, diaphragm, spermicide) to prevent pregnancy while taking tipranavir.|
|Women with HIV or AIDS should not breast-feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.|
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
If you also take ritonavir, take it at the same time you take tipranavir unless your doctor has told you otherwise.
|Tipranavir works best if you take it with food. Swallow the capsule whole. Do not break or chew it.|
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
To be sure this medicine is helping your condition and is not causing harmful effects, your blood will need to be tested often. Your liver function may also need to be tested. Visit your doctor regularly.
|If you need surgery, tell the surgeon ahead of time that you are using tipranavir.|
Use tipranavir regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
HIV/AIDS is usually treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor's advice. Every person with HIV or AIDS should remain under the care of a doctor.
Store an unopened bottle of tipranavir capsules in the refrigerator. Do not freeze. After opening the bottle for the first time, you may store the capsules at room temperature. Throw away any capsules you have not used within 60 days after you first opened the medicine bottle.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
|Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.|
If you also take didanosine, take it 2 hours before or after you take tipranavir.
|Taking this medication will not prevent you from passing HIV to other people. Avoid having unprotected sex or sharing razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.|
|Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.|
|Some people taking tipranavir and ritonavir have developed life-threatening medical problems including liver damage and bleeding in the brain. If you are taking these two medications, call your doctor at once if you have any of the following side effects:|
|Stop taking tipranavir and call your doctor at once if you have any of these serious side effects:|
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Many drugs can interact with tipranavir. Below is just a partial list. Tell your doctor if you are using:
This list is not complete and there are many other drugs that can interact with tipranavir. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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