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|Pronunciation:||eye byoo PROE fen and ox i KOE done|
|This medicine may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term. Do not use ibuprofen and oxycodone just before or after heart bypass surgery (coronary artery bypass graft, or CABG). Get emergency medical help if you have chest pain, weakness, shortness of breath, slurred speech, or problems with vision or balance.|
|This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen and oxycodone, especially in older adults. Call your doctor at once if you have symptoms of stomach bleeding such as black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds.|
|Oxycodone may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.|
|Avoid drinking alcohol. It may increase your risk of stomach bleeding.|
Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Oxycodone is an opioid pain medication. An opioid is sometimes called a narcotic.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body.
The combination of ibuprofen and oxycodone is used short-term to relieve moderate to severe pain.
Ibuprofen and oxycodone may also be used for purposes not listed in this medication guide.
|You should not use this medication if you have severe or uncontrolled asthma, or a stomach condition called paralytic ileus. Do not use ibuprofen and oxycodone just before or after heart bypass surgery (coronary artery bypass graft, or CABG).|
|Oxycodone may be habit forming and should be used only by the person it was prescribed for. Never share this medication with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.|
|Ibuprofen may cause life-threatening heart or circulation problems such as heart attack or stroke, especially if you use it long term.|
This medicine may also cause serious effects on the stomach or intestines, including bleeding or perforation (forming of a hole). These conditions can be fatal and can occur without warning while you are taking ibuprofen and oxycodone, especially in older adults.
|Do not use this medication if you are allergic to oxycodone or ibuprofen (Advil, Motrin), or other NSAIDs such as aspirin, Aleve, Celebrex, Orudis, Indocin, Lodine, Voltaren, Toradol, Mobic, Relafen, Feldene, and others.|
To make sure you can safely take ibuprofen and oxycodone, tell your doctor if you have any of these other conditions:
|FDA pregnancy category D. Oxycodone may cause breathing problems and addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Taking ibuprofen during the last 3 months of pregnancy may harm the unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using ibuprofen and oxycodone.|
|Ibuprofen and oxycodone may pass into breast milk and could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.|
Older adults may be more sensitive to the effects of this medicine.
Take exactly as prescribed. Never take ibuprofen and oxycodone in larger amounts, or for longer than recommended by your doctor. Follow the directions on your prescription label. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
|Drink 6 to 8 full glasses of water daily to help prevent constipation while you are taking ibuprofen and oxycodone. Ask your doctor about ways to increase the fiber in your diet. Do not use a stool softener (laxative) without first asking your doctor.|
|If you need surgery, tell the surgeon ahead of time that you are using ibuprofen and oxycodone.|
|Store at room temperature away from moisture and heat.|
Keep track of the amount of medicine used from each new bottle. Ibuprofen and oxycodone is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Since ibuprofen and oxycodone is taken as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
|Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of ibuprofen and oxycodone can be fatal.|
Overdose symptoms may include extreme drowsiness, nausea, vomiting, dark urine, jaundice (yellowing of the skin or eyes), black or bloody stools, coughing up blood, urinating less than usual or not at all, confusion, ringing in your ears, pinpoint pupils, weak pulse, slow heart rate, fainting, blue lips, shallow breathing.
|This medication may impair your thinking or reactions. Avoid driving or operating machinery until you know how ibuprofen and oxycodone will affect you.|
|Ask a doctor or pharmacist before using any other cold, allergy, or pain medicine. Ibuprofen is contained in many combination medicines. Taking certain products together can cause you to get too much ibuprofen. Check the label to see if a medicine contains ibuprofen.|
|Avoid drinking alcohol. It may increase your risk of stomach bleeding.|
|Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.|
|Stop using ibuprofen and oxycodone and call your doctor at once if you have a serious side effect such as:|
Less serious side effects include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
|Before using this medicine, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, sedatives, other narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by oxycodone.|
Also tell your doctor if you are using any of the following drugs:
This list is not complete and other drugs may interact with ibuprofen and oxycodone. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your pharmacist can provide more information about ibuprofen and oxycodone.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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