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exemestane

Pronunciation: ex e MES tane

Brand: Aromasin

Aromasin 25 mg

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Image of Aromasin 25 mg
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What is the most important information I should know about exemestane?

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Do not use exemestane if you are pregnant. It could harm the unborn baby or cause a miscarriage.

You may need to take a pregnancy test before using exemestane, to make sure you are not pregnant.

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You should not use this medication if you are allergic to exemestane, or if you are breast-feeding a baby.

Before using exemestane, tell your doctor if you have liver or kidney disease, or if you have not yet completed menopause and are still having menstrual periods.

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Use exemestane regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You may need to keep taking take this medication for up to 5 years. Follow your doctor's instructions.

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Exemestane may not work as well if you take it together with hormone replacement medication, or while using birth control pills or patches.

What is exemestane?

Exemestane lowers estrogen levels in postmenopausal women, which may slow the growth of certain types of breast tumors that need estrogen to grow in the body.

Exemestane is used to treat breast cancer in postmenopausal women. It is often given to women whose cancer has progressed even after taking tamoxifen (Nolvadex, Soltamox) for 2 to 3 years.

Exemestane may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before taking exemestane?

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You should not use this medication if you are allergic to exemestane, or if you are breast-feeding a baby.

To make sure you can safely take exemestane, tell your doctor if you have any of these other conditions:

  • liver disease;
  • kidney disease; or
  • if you have not yet completed menopause, and are still having menstrual periods.
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Exemestane can decrease bone mineral density, which may increase your risk of developing osteoporosis. Talk to your doctor about your individual risk of bone loss.

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FDA pregnancy category D. Do not use exemestane if you are pregnant. It could harm the unborn baby or cause a miscarriage. Use effective birth control, and tell your doctor if you become pregnant during treatment.

You may need to take a pregnancy test before using exemestane, to make sure you are not pregnant.

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It is not known whether exemestane passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take exemestane?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Exemestane is usually taken once per day, after a meal. Try to take the medicine at the same time each day.

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Use exemestane regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely. You may need to keep taking take this medication for up to 5 years. Follow your doctor's instructions.

To be sure this medication is not causing harmful effects, your blood may need to be tested often. Visit your doctor regularly.

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Store in the original container at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking exemestane?

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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

What are the possible side effects of exemestane?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have a serious side effect such as:

  • new or unusual bone pain;
  • vision problems;
  • swelling in your hands or feet;
  • feeling short of breath, even with mild exertion; or
  • chest pain, sudden numbness or weakness, sudden headache, confusion, problems with vision, speech, or balance.

Less serious side effects may include:

  • hot flashes;
  • headache, tired feeling;
  • anxiety;
  • joint pain;
  • upset stomach;
  • depressed mood;
  • sleep problems (insomnia); or
  • increased sweating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect exemestane?

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Exemestane may not work as well if you take it together with hormone replacement medication, or while using birth control pills or patches.

Tell your doctor about all other medicines you use, especially:

  • bosentan (Tracleer);
  • dexamethasone (Decadron, Hexadrol);
  • St. John's wort;
  • rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), or rifapentine (Priftin);
  • a barbiturate such as butabarbital (Butisol), secobarbital (Seconal), pentobarbital (Nembutal), or phenobarbital (Luminal, Solfoton);
  • HIV medication such as efavirenz (Sustiva, Atripla), etravirine (Intelence), nevirapine (Viramune), or ritonavir (Norvir, Kaletra);
  • medicines to treat narcolepsy, such as armodafinil (Nuvigil) or modafinil (Progivil); or
  • seizure medication such as carbamazepine (Carbatrol, Tegretol), felbamate (Felbatol), oxcarbazepine (Trileptal), phenytoin (Dilantin), or primidone (Mysoline).

This list is not complete and other drugs may interact with exemestane. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about exemestane.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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