If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: peg ah SPAR jase
Do not receive this medication if you are allergic to pegaspargase, or if you have ever been treated with asparaginase (Elspar) and had a severe allergic reaction or developed a stroke, blood clot, or pancreas problems.
Before receiving pegaspargase, tell your doctor if you are allergic to any drugs, or if you have diabetes or a bleeding disorder such as hemophilia.
While receiving pegaspargase, avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.
Get emergency medical help if you think you have received too much of this medicine, or if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of the following side effects during your treatment with pegaspargase:
Pegaspargase is a cancer medication that interferes with the growth of cancer cells and slows their growth and spread in the body.
Pegaspargase is used to treat acute lymphoblastic leukemia.
Pegaspargase may also be used for purposes other than those listed in this medication guide.
Do not receive this medication if you are allergic to pegaspargase, or if you have ever been treated with asparaginase (Elspar) and had:
Before receiving pegaspargase, tell your doctor if you are allergic to any drugs, or if you have:
If you have any of these conditions, you may not be able to receive pegaspargase, or you may need a dosage adjustment or special tests during treatment.
FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
It is not known whether pegaspargase passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Pegaspargase is given as an injection through an IV needle placed into a vein, or as a shot into a muscle. You will receive this injection in a clinic or hospital setting. The IV medicine must be given slowly, and it can take up to 2 hours to complete.
After receiving this medication, your doctor may want to observe you for at least 1 hour to make sure the medication does not cause harmful side effects.
Before you receive your first treatment with this medication, you may need a skin test to make sure you are not allergic to pegaspargase.
Pegaspargase can lower the blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. To be sure your blood cells do not get too low, your blood will need to be tested on a regular basis. Do not miss any scheduled visits to your doctor.
This medication can cause you to have unusual results with certain thyroid tests. Tell any doctor who treats you that you are receiving pegaspargase.
Contact your doctor if you miss an appointment for your pegaspargase injection.
Seek emergency medical attention if you think you have received too much of this medicine. Symptoms of a pegaspargase overdose may include easy bruising or bleeding, unusual weakness, nausea, loss of appetite, and jaundice (yellowing of the skin or eyes).
Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have any of these serious side effects:
Less serious side effects may be more likely to occur, such as:
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Before receiving asparaginse, tell your doctor if you are using any of the following drugs:
If you are using any of these drugs, you may not be able to receive pegaspargase, or you may need dosage adjustments or special tests during treatment.
There may be other drugs not listed that can affect pegaspargase. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
Your pharmacist has information about pegaspargase written for health professionals that you may read.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 1.07. Revision date: 12/15/2010.
Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.