If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: RE te plase
You should not receive this medication if you are allergic to retaplase, or if you have a bleeding disorder, a brain tumor or aneurysm, uncontrolled high blood pressure, a history of stroke or blood clots, or recent brain or spinal injury or surgery.
Before using retaplase, tell your doctor if you have kidney or liver disease, eye complications caused by diabetes, an infection of the lining of your heart, or if you have had any recent surgery, injury, or major bleeding.
Tell your doctor if you take aspirin, a blood thinner such as warfarin (Coumadin), or any medications to prevent blood clots, such as abciximab (ReoPro), dipyridamole (Persantine), and others.
Tell your doctor at once if you have a serious side effect such as sudden numbness or weakness, confusion, problems with speech or vision, chest pain, sudden cough, wheezing, rapid breathing, fast or slow heart rate, darkening or purple discoloration of your fingers or toes, blood in your urine or stools, pale skin, easy bruising, or any bleeding that will not stop.
Retaplase is a thrombolytic (THROM-bo-LIT-ik) drug that is used to dissolve blood clots.
Retaplase is used to improve heart function and prevent congestive heart failure or death in people who have had a heart attack.
Retaplase may also be used for other purposes not listed in this medication guide.
You should not receive this medication if you are allergic to retaplase, or if you have certain conditions. Be sure your doctor knows if you have:
Before you receive retaplase, tell your doctor if you are allergic to any drugs, or if you have:
If you have any of these conditions, you may need a dose adjustment or special tests to safely receive this medicaiton.
FDA pregnancy category C. Retaplase may be harmful to an unborn baby. Before receiving this medication, tell your doctor if you are pregnant.
It is not known whether retaplase passes into breast milk or if it could harm a nursing baby. Do not receive this medication without telling your doctor if you are breast-feeding a baby.
Retaplase is given as an injection through a needle placed into a vein. You will receive this injection in a clinic or hospital setting.
Retaplase is usually given in two quick injections through an IV line. These injection are given 30 minutes apart.
This medication can cause you to have unusual results with certain medical tests. Tell any doctor who treats you that you have received retaplase.
Since retaplase is given only when needed by a healthcare professional, it is not likely that you will miss a dose.
Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using retaplase.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.
The following drugs can interact with retaplase. Tell your doctor if you are using any of these:
This list is not complete and there may be other drugs that can interact with retaplase. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.
Your doctor or pharmacist can provide more information about retaplase.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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