potassium gluconate

Pronunciation: poe TASS ee um GLOO koe nate

Brand: Kaon

What is the most important information I should know about potassium gluconate?

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You should not use this medication if you have kidney failure, a urinary tract infection, uncontrolled diabetes, a peptic ulcer in your stomach, Addison's disease, severe burns or other tissue injury, if you are dehydrated, if you take certain diuretics (water pills), or if you have high levels of potassium in your blood (hyperkalemia).

You should not take potassium gluconate tablets if you have problems with your esophagus, stomach, or intestines that make it difficult for you to swallow or digest pills.

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Do not chew or suck on a potassium tablet. It can irritate your mouth or throat. Swallow the tablet whole with a full glass (at least 8 ounces) of water.

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Avoid lying down for at least 30 minutes after you take this medication.

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Take this medication with food or just after a meal.

To be sure this medication is helping your condition, your blood may need to be tested often. Your heart rate may also be checked using an electrocardiograph or ECG (sometimes called an EKG) to measure electrical activity of the heart. This test will help your doctor determine how long to treat you with potassium. Do not miss any scheduled appointments.

Serious side effects of potassium include uneven heartbeat, muscle weakness or limp feeling, severe stomach pain, and numbness or tingling in your hands, feet, or mouth.

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Do not stop taking this medication without first talking to your doctor. If you stop taking potassium suddenly, your condition may become worse.

What is potassium gluconate?

Potassium is a mineral that is found in many foods and is needed for several functions of your body, especially the beating of your heart.

Potassium gluconate is used to prevent or to treat low blood levels of potassium (hypokalemia). Potassium levels can be low as a result of a disease or from taking certain medicines, or after a prolonged illness with diarrhea or vomiting.

Potassium gluconate may also be used for other purposes other than those listed in this medication guide.

What should I discuss with my healthcare provider before taking potassium gluconate?

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You should not use this medication if you are allergic to it, or if you have certain conditions. Be sure your doctor knows if you have:

  • high levels of potassium in your blood (hyperkalemia);
  • kidney failure;
  • Addison's disease (an adrenal gland disorder);
  • a large tissue injury such as a severe burn;
  • if you are severely dehydrated; or
  • if you are taking a "potassium-sparing" diuretic (water pill) such as amiloride (Midamor, Moduretic), spironolactone (Aldactone, Aldactazide), triamterene (Dyrenium, Dyazide, Maxzide).

You should not take potassium gluconate tablets if you have problems with your esophagus, stomach, or intestines that make it difficult for you to swallow or digest pills.

Before using potassium gluconate, tell your doctor if you are allergic to any drugs, or if you have:

  • kidney disease;
  • heart disease, an enlarged heart, or high blood pressure;
  • a blockage in your stomach or intestines; or
  • chronic diarrhea (such as ulcerative colitis, Crohn's disease).

If you have any of these conditions, you may need a dose adjustment or special tests to safely take potassium gluconate.

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FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

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It is not known whether potassium passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take potassium gluconate?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

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Do not chew or suck on a potassium tablet. It can irritate your mouth or throat. Swallow the tablet whole with a full glass (at least 8 ounces) of water. Call your doctor if it feels like the tablet is getting stuck in your throat when you swallow it.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

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Liquid potassium should be mixed with water or fruit juice before taking. Follow the medicine label directions about how much water or juice to use.

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Take this medication with food or just after a meal.

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Your treatment may include a special diet. It is very important to follow the diet plan created for you by your doctor or nutrition counselor. You should become very familiar with the list of foods you should eat or avoid to help control your condition.

To be sure this medication is helping your condition, your blood may need to be tested often. Your heart rate may also be checked using an electrocardiograph or ECG (sometimes called an EKG) to measure electrical activity of the heart. This test will help your doctor determine how long to treat you with potassium. Do not miss any scheduled appointments.

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Do not stop taking this medication without first talking to your doctor. If you stop taking potassium suddenly, your condition may become worse.

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Store potassium gluconate at room temperature away from moisture and heat. Keep the medication in a closed container.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, muscle weakness, numbness or tingling, chest pain, uneven heartbeat, or feeling like you might pass out.

What should I avoid while taking potassium gluconate?

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Avoid lying down for at least 30 minutes after you take this medication.

Avoid taking potassium supplements or using other products that contain potassium without first asking your doctor. Salt substitutes or low-salt dietary products often contain potassium. If you take certain products together you may accidentally get too much potassium. Read the label of any other medicine you are using to see if it contains potassium.

What are the possible side effects of potassium gluconate?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Stop using this medication and call your doctor at once if you have any of these serious side effects:

  • confusion, anxiety, feeling like you might pass out;
  • uneven heartbeat;
  • extreme thirst, increased urination;
  • leg discomfort;
  • muscle weakness or limp feeling;
  • numbness or tingly feeling in your hands or feet, or around your mouth;
  • severe stomach pain, ongoing diarrhea or vomiting;
  • black, bloody, or tarry stools; or
  • coughing up blood or vomit that looks like coffee grounds.

Less serious side effects may include:

  • mild nausea or upset stomach;
  • mild or occasional diarrhea; or
  • slight tingling in your hands or feet.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect potassium gluconate?

The following drugs can interact with potassium gluconate. Tell your doctor if you are using any of these:

  • eplerenone (Inspra);
  • digoxin (digitalis, Lanoxin);
  • candesartan (Atacand), losartan (Cozaar, Hyzaar), valsartan (Diovan), or telmisartan (Micardis);
  • glycopyrrolate (Robinul);
  • mepenzolate (Cantil);
  • quinidine (Quinaglute, Quinidex, Quin-Release);
  • atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);
  • a bronchodilator such as ipratroprium (Atrovent) or tiotropium (Spiriva);
  • bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);
  • irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine);
  • an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace), or trandolapril (Mavik); or
  • any type of diuretic (water pill) such as bumetanide (Bumex), chlorothiazide (Diuril), chlorthalidone (Hygroton, Thalitone), ethacrynic acid (Edecrin), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), indapamide (Lozol), metolazone (Mykrox, Zarxolyn), or torsemide (Demadex).

This list is not complete and there may be other drugs that can interact with potassium gluconate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about potassium gluconate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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