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| Pronunciation: | HYE droe klor oh THYE a zide and bi SOE proe lol |
| Brand: | Ziac |
oblong, white, imprinted with 652, R

round, white, imprinted with 843, WATSON

round, yellow, imprinted with 841, WATSON

round, pink, imprinted with 842, WATSON

round, white, imprinted with E 707

round, white, imprinted with 505, M

round, peach, imprinted with E 701

round, orange, imprinted with 501, M

round, red, imprinted with E 704

round, blue, imprinted with 503, M

round, white, imprinted with LL, B 14

round, white, imprinted with b, 40

round, yellow, imprinted with LL, B 12

round, yellow, imprinted with b, 47

round, pink, imprinted with LL, B 13

round, pink, imprinted with b, 50

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You should not use this medication if you have severe or uncontrolled heart failure, a heart condition called "sick sinus syndrome" or "AV block," slow heartbeats, an allergy to sulfa drugs, or if you are unable to urinate. |
Before using this medication, tell your doctor if you have congestive heart failure, circulation problems, kidney or liver disease, cirrhosis, glaucoma, asthma, bronchospastic lung disease, a thyroid disorder, lupus, gout, diabetes, or a penicillin allergy.
If you are diabetic, check your blood sugar carefully. Using bisoprolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking hydrochlorothiazide and bisoprolol. Talk with your doctor before changing any doses.
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Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and bisoprolol. |
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
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Keep using this medication even if you feel fine. High blood pressure often has no symptoms. |
There are many other medicines that can interact with hydrochlorothiazide and bisoprolol. Tell your doctor about all the prescription and over-the-counter medications you use.
Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.
Bisoprolol is a beta-blocker. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).
The combination of hydrochlorothiazide and bisoprolol is used to treat high blood pressure (hypertension).
Hydrochlorothiazide and bisoprolol may also be used for purposes not listed in this medication guide.
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You should not use this medication if you are allergic to hydrochlorothiazide or bisoprolol, or if you have: |
To make sure you can safely take hydrochlorothiazide and bisoprolol, tell your doctor if you have any of these other conditions:
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FDA pregnancy category C. It is not known whether hydrochlorothiazide and bisoprolol will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. |
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Hydrochlorothiazide can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using hydrochlorothiazide and bisoprolol. |
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
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Take the medicine with a meal or right after you eat. |
Your doctor may occasionally change your dose to make sure you get the best results.
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Do not stop using hydrochlorothiazide and bisoprolol suddenly, or you could have a serious or life-threatening heart problem. Talk to your doctor about how to avoid withdrawal symptoms when stopping the medication. |
Your blood pressure will need to be checked often. Your blood and urine may both be tested if you have been vomiting or are dehydrated. Visit your doctor regularly.
If you are diabetic, check your blood sugar carefully. Using bisoprolol can make it harder for you to tell when you have low blood sugar. Your insulin or diabetic medication needs may change while you are taking hydrochlorothiazide and bisoprolol. Talk with your doctor before changing any doses.
Hydrochlorothiazide and bisoprolol can affect the results of certain thyroid tests. Tell any doctor who treats you that you are using this medication.
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If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and bisoprolol. You may need to stop using the medicine for a short time. |
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Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. |
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Store in a tightly closed container at room temperature, away from heat, moisture, and light. |
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. |
Overdose symptoms may include fast or slow heart rate, confusion, weakness, shallow breathing, swelling, increased urination, and feeling like you might pass out.
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Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and bisoprolol. |
Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
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This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. |
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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. |
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Stop using this medication and call your doctor at once if you have any of these serious side effects: |
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
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Tell your doctor if you regularly use any other medicines that make you light-headed (especially narcotic pain medication or barbiturates). They can add to the side effects of hydrochlorothiazide and bisoprolol. |
Many drugs can interact with hydrochlorothiazide and bisoprolol. Below is just a partial list. Tell your doctor if you are using:
This list is not complete and other drugs may interact with hydrochlorothiazide and bisoprolol. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your pharmacist can provide more information about hydrochlorothiazide and bisoprolol.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01. Revision date: 5/10/2011.
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