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Pronunciation: KOE deen and proe METH a zeen
Brand: Codeine Phosphate-Promethazine HCl, Promethazine HCl and Codeine Phosphate, Promethazine with Codeine
Tell your doctor about all of your medical conditions before you start taking this medication.
You should not use this medication if you are allergic to codeine or promethazine, or if you have asthma or other lung disease.
Codeine and promethazine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it.
Do not give this medication to a child without medical advice.
There are many other medicines that can cause interact with promethazine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.
Codeine is a narcotic. It is a pain reliever and a cough suppressant.
Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.
The combination of codeine and promethazine is used to treat cold or allergy symptoms such as runny nose, sneezing, and cough.
Codeine and promethazine may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to codeine or promethazine, or if you have high blood pressure, a blood vessel disorder, or asthma.
Do not give this medication to a child without medical advice. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.
To make sure you can safely take codeine and promethazine, tell your doctor if you have any of these other conditions:
Codeine and promethazine may be habit forming and should be used only by the person it was prescribed for. Never share codeine and promethazine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.
FDA pregnancy category C. It is not known whether codeine and promethazine will harm an unborn baby. Codeine and promethazine may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using codeine and promethazine.
Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Contact your doctor if your symptoms do not improve within a few days of using codeine and promethazine.
Store at room temperature away from moisture, heat, and light.
Keep track of the amount of medicine used from each new bottle. Codeine and promethazine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of this medication may be fatal.
Overdose symptoms include dizziness, extreme drowsiness, dry mouth, nausea, vomiting, cold and clammy skin, weak pulse, shallow breathing, fainting, seizure (convulsions), or breathing that stops.
This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Drinking alcohol can increase certain side effects of codeine and promethazine.
Avoid exposure to sunlight or tanning beds. Codeine and promethazine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, other pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine and promethazine.
Many drugs can interact with codeine and promethazine. Below is just a partial list. Tell your doctor if you are using:
This list is not complete and other drugs may interact with codeine and promethazine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your pharmacist can provide more information about codeine and promethazine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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