If you are experiencing a medical emergency please dial 911 immediately
Pronunciation: KLAD ri been
Brand: Cladribine Novaplus, Leustatin
Do not use cladribine if you are pregnant. It could harm the unborn baby.
Before you receive cladribine, tell your doctor If you have liver or kidney disease or a bone marrow problem.
Cladribine can lower blood cells that help your body fight infections and help your blood to clot. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while using cladribine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you.
Tell your caregivers at once if you have a serious side effect such as numbness or tingling, weakness or burning pain in your fingers or toes, lower back pain, blood in your urine, urinating less than usual, muscle weakness or tightness, pale or yellowed skin, easy bruising or bleeding, dark colored urine, or feeling like you might pass out.
Cladribine is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Cladribine is used to treat hairy cell leukemia (a type of blood cancer).
Cladribine may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to it.
To make sure cladribine is safe for you, tell your doctor if you have liver or kidney disease, or a bone marrow problem.
FDA pregnancy category D. Do not use cladribine if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
It is not known whether cladribine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are receiving cladribine.
Cladribine is injected into a vein through an IV. You will receive this injection in a clinic or hospital setting.
Cladribine must be given slowly through an IV infusion, and you will receive it around the clock for 7 days in a row. Your doctor will determine how many 7- day treatments you will receive and how often.
You may receive other medications to help prevent certain side effects of cladribine.
Cladribine can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.
Contact your doctor at once if you develop signs of infection such as fever, chills, sore throat, flu symptoms, cough with yellow or green mucus, loss of appetite, mouth sores, unusual weakness.
Since this medication is given in a healthcare setting around the clock, you will not miss a dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while using cladribine, and avoid coming into contact with anyone who has recently received a live vaccine. There is a chance that the virus could be passed on to you. Live vaccines include measles, mumps, rubella (MMR), Bacillus Calmette-Guérin (BCG), oral polio, rotavirus, smallpox, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
Less serious side effects may include:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Tell your doctor about all other medications you use, especially drugs that weaken your immune system such as:
This list is not complete and other drugs may interact with cladribine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your doctor or pharmacist can provide more information about cladribine.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
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