colistimethate

Pronunciation: koe LIS ti METH ate

Brand: Coly Mycin M

What is the most important information I should know about colistimethate?

Multum donot

You should not use this medication if you are allergic to colistimethate.

Before using colistimethate, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need a dose adjustment or special tests during treatment.

Colistimethate is given as an injection into a muscle or through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

Keep using colistimethate for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Colistimethate will not treat a viral infection such as the common cold or flu.

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If you need to have any type of surgery, tell the surgeon ahead of time that you are using colistimethate. You may need to stop using the medicine for a short time.

What is colistimethate?

Colistimethate is an antibiotic that fights bacteria in the body.

Colistimethate is used to treat infections caused by bacteria.

Colistimethate may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking colistimethate?

Multum donot

You should not use this medication if you are allergic to colistimethate.

Before using colistimethate, tell your doctor if you are allergic to any drugs, or if you have kidney disease. You may need dose adjustments or special tests during treatment.

Your doctor will tell you if any of your medication doses need to be changed.

Multum nopreg

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether colistimethate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take colistimethate?

Colistimethate is given as an injection into a muscle or through a needle placed into a vein. Your doctor, nurse, or other healthcare provider will give you this injection. You may be shown how to inject your medicine at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles and syringes.

The colistimethate injection is sometimes given every 12 hours. The medication can also be mixed with a liquid in an IV bag and given as a slow infusion over a 24-hour period.

Use each disposable needle and syringe only one time. Throw away used needles and syringes in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.

Use this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Keep using colistimethate for the full prescribed length of time. Your symptoms may improve before the infection is completely cleared. Colistimethate will not treat a viral infection such as the common cold or flu.

Multum emt

If you need to have any type of surgery, tell the surgeon ahead of time that you are using colistimethate. You may need to stop using the medicine for a short time.

Multum rt

If you store colistimethate at home, keep the medication at cool room temperature away from moisture and heat.

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After colistimethate is mixed in an IV bag, it must be kept in a refrigerator and used within 7 days of mixing.

What happens if I miss a dose?

Use the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Multum emt

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include confusion, dizziness, loss of balance or coordination, blurred vision, slurred speech, severe numbness or tingling, or trouble breathing.

What should I avoid while taking colistimethate?

Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or has blood in it, call your doctor. Do not use any medicine to stop the diarrhea unless your doctor has told you to.

What are the possible side effects of colistimethate?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Call your doctor at once if you have any of these serious side effects:

  • diarrhea that is watery or bloody;
  • fever;
  • urinating less than usual or not at all;
  • muscle weakness; or
  • trouble breathing.

Less serious side effects may include:

  • mild numbness or tingling in your hands or feet;
  • dizziness, spinning feeling;
  • itching, mild skin rash; or
  • upset stomach.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect colistimethate?

The following antibiotics can interact with colistimethate. Tell your doctor if you are using any of these:

  • amikacin (Amikin);
  • gentamicin (Garamycin);
  • kanamycin (Kantrex);
  • neomycin (Mycifradin, Neo-Fradin, Neo-Tab);
  • netilmicin (Netromycin);
  • polymyxin;
  • streptomycin; or
  • tobramycin (Nebcin, Tobi).

This list is not complete and there may be other drugs that can interact with colistimethate. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about colistimethate.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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