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methylphenidate (transdermal)

Pronunciation: meth il FEN ih date

Brand: Daytrana

What is the most important information I should know about methylphenidate transdermal?

Do not use methylphenidate if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

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You should not use this medicine if you are allergic to methylphenidate or if you have glaucoma, tics (muscle twitches) or Tourette's syndrome, or severe anxiety, tension, or agitation (methylphenidate can make these symptoms worse).

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Methylphenidate may be habit forming. Never share methylphenidate with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it.

Keep track of the amount of patches used from each new package. Methylphenidate is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription. Using methylphenidate improperly can cause death or serious side effects on the heart.

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Children using this medication should be warned never to remove the skin patch and place it onto another person. Serious side effects may result.

What is methylphenidate transdermal?

Methylphenidate is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control.

Methylphenidate is used to treat attention deficit hyperactivity disorder (ADHD).

Methylphenidate may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before using methylphenidate transdermal?

Do not use methylphenidate if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include furazolidone, isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not use this medication if you are allergic to methylphenidate or if you have:

  • glaucoma;
  • a personal or family history of tics (muscle twitches) or Tourette's syndrome;
  • severe anxiety, tension, or agitation (methylphenidate can make these symptoms worse); or
  • if you have ever had a skin reaction when using any type of adhesive bandage or transdermal skin patch.
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Some stimulants have caused sudden death in children and adolescents with serious heart problems or congenital heart defects. To make sure methylphenidate is safe for you, tell your doctor if you have:

  • a congenital heart defect;
  • high blood pressure, heart failure, heart rhythm disorder, or recent heart attack;
  • a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt;
  • epilepsy or other seizure disorder;
  • a skin condition such as eczema or psoriasis; or
  • a history of drug or alcohol addiction.
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Methylphenidate may be habit forming. Never share methylphenidate with another person, especially someone with a history of drug abuse or addiction.

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FDA pregnancy category C. It is not known whether methylphenidate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

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It is not known whether methylphenidate passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Long-term use of methylphenidate can slow a child's growth. Tell your doctor if the child using this medication is not growing or gaining weight properly.

Do not use methylphenidate transdermal on a child younger than 6 years old without the advice of a doctor.

How should I use methylphenidate transdermal?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended. This medication comes with patient instructions for safe and effective use. Ask your doctor or pharmacist if you have any questions.

To use the patch, open the sealed pouch and remove the protective liner. Press the patch onto the skin and press it down with the palm of your hand for about 30 seconds. Make sure the patch is well sealed around the edges. When properly applied, the patch should stay on while swimming or bathing.

Apply the patch to an area on the hip that is clean and dry. Avoid skin that is oily, irritated, or damaged. Avoid a skin area that will be rubbed by a waistband or tight clothing. The next morning, apply a new patch to the opposite hip. Do not wear a patch on the same side of the body two days in a row.

The effects of this medicine may not be noticeable until 2 hours after applying the skin patch. Remove the patch 9 hours after it was applied.

If the patch falls off, replace it with a new one. Then remove the new patch after it has been 9 hours since you applied the first patch. Your patch wearing time should be no more than 9 hours per day, even if you apply a new patch to replace one that has fallen off.

After removing a patch, fold it in half so it sticks together and flush it down the toilet or place it in a waste can with a lid. If you stop using this medicine and have any unused patches leftover, throw each patch away using this same method.

Methylphenidate transdermal patches come with a chart to keep track of when the patches are applied and removed. A time chart is also included to help you estimate what time to remove a patch based on what time it is applied.

If you have sleep problems (insomnia) or loss of appetite in the evenings, try removing the skin patch earlier in the day. Never cut the skin patch to try and reduce the amount of medicine you receive while wearing it.

Do not expose the skin patch to heat while you are wearing it. This includes heat from a heating pad, hot tub, electric blanket, or a heated water bed. Heat can cause the skin patch to release too much medicine at one time.

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Keep the methylphenidate transdermal patch in its sealed pouch until you are ready to use it. Store at room temperature away from heat and moisture. Throw away any unused patches that are left over if it has been more than 30 days since you opened the original package.

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Methylphenidate is a drug of abuse and may be habit-forming. Keep track of how many patches have been used from each new package you receive. You should be aware if anyone is using your medicine improperly or without a prescription. Using this medication improperly can cause death or serious side effects on the heart.

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Children using this medication should be warned never to remove the skin patch and place it onto another person. Serious side effects may result.

What happens if I miss a dose?

Apply a patch as soon as you remember, and do not wear the patch for longer than 9 hours. You may need to shorten the wearing time to less than 9 hours if you apply a patch later than usual and you have sleep problems. Do not apply two patches at the same time to make up the missed dose.

What happens if I overdose?

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Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Remove the patch right away and clean the skin area with soap and water. An overdose of methylphenidate can be fatal.

What should I avoid while using methylphenidate transdermal?

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Methylphenidate may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Do not apply a patch late in the day. A patch applied too late in the day can cause sleep problems (insomnia).

What are the possible side effects of methylphenidate transdermal?

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

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Stop using methylphenidate and call your doctor at once if you have:

  • fast, pounding, or uneven heartbeats, feeling light-headed, fainting;
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, shortness of breath, seizure);
  • redness, swelling, itching, or blistering where the skin patch was worn (may also spread to other areas);
  • headache with fever, weakness, joint pain, diarrhea, and/or vomiting;
  • aggression, restlessness, hallucinations, unusual behavior, or motor tics (muscle twitches); or
  • confusion, crying, feeling irritable.

Common side effects may include:

  • vision problems;
  • mild skin redness, bumps, or itching;
  • nausea, loss of appetite, weight loss;
  • sleep problems (insomnia); or
  • stuffy nose, sore throat.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect methylphenidate transdermal?

Tell your doctor about all medicines you use, and those you start or stop using during your treatment with methylphenidate, especially:

  • clonidine or other blood pressure medications;
  • a blood thinner such as warfarin, Coumadin;
  • seizure medicine--phenytoin, phenobarbital, primidone; or
  • an antidepressant--clomipramine, desipramine, imipramine, citalopram, fluoxetine, paroxetine, and others.

This list is not complete. Other drugs may interact with methylphenidate, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

Your pharmacist can provide more information about methylphenidate transdermal.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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