esterified estrogens
| Pronunciation: | ess TER ih fied ESS troe jenz |
| Brand: | Estratab, Menest |
Estratab 0.625 mg
round, yellow, imprinted with SOLVAY 1022
Menest 0.3 mg
oblong, yellow, imprinted with BMP 125
Menest 0.625 mg
oblong, orange, imprinted with BMP 126
Menest 1.25 mg
oblong, green, imprinted with BMP 127
What is the most important information I should know about esterified estrogens?
Esterified estrogens increase the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with esterified estrogens lowers the risk of developing this condition. Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen. Visit your doctor regularly and report any unusual vaginal bleeding right away.
Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking esterified estrogens.
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Do not take esterified estrogens if you are pregnant. |
Who should not take esterified estrogens?
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Do not take esterified estrogens without first talking to your doctor if you have |
- a circulation, bleeding, or blood-clotting disorder;
- undiagnosed, abnormal vaginal bleeding; or
- any type of breast, uterine, or hormone-dependent cancer.
Taking esterified estrogens may be dangerous in some cases if you have any of the conditions listed above.
Before taking esterified estrogens, tell your doctor if you have
- high blood pressure, angina, or heart disease;
- high levels of cholesterol or triglycerides in your blood;
- liver disease;
- kidney disease;
- asthma;
- epilepsy;
- migraines;
- diabetes;
- depression;
- gallbladder disease;
- uterine fibroids; or
- had a hysterectomy (uterus removed).
You may not be able to take esterified estrogens, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions listed above.
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Esterified estrogens are in the FDA pregnancy category X. This means that esterified estrogens will cause birth defects in an unborn baby. Do not take this medication if you are pregnant or are planning a pregnancy. |
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Esterified estrogens may decrease milk flow and have other effects on milk composition. Do not use this medication without first talking to your doctor if you are breast-feeding a baby. |
How should I take esterified estrogens?
Take this medication exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
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Take each dose with a full glass of water. |
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Take esterified estrogens with food or milk to lessen stomach upset. |
Try to take every dose at the same time each day. You may be taking it every day, or you may be taking it every day for 3 weeks with 1 week off each month to mimic your body's natural cycle. Follow the directions on your prescription label.
If you are taking esterified estrogens to treat cancer, you may be taking it several times a day in very large doses.
Have yearly physical exams and examine your breasts for lumps on a monthly basis while taking esterified estrogens.
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Store esterified estrogens at room temperature away from moisture and heat. |
What happens if I overdose?
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An overdose of this medication is unlikely to threaten life. Consult an emergency room or poison control center for advice. |
Symptoms of an overdose of esterified estrogens include nausea, vomiting, and breakthrough bleeding in females.
What are the possible side effects of esterified estrogens?
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If you experience any of the following serious side effects, stop taking esterified estrogens and seek emergency medical attention: |
- an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
- a blood clot (pain, redness, and swelling in an arm or leg, shortness of breath, chest pain, headache, blurred vision, or confusion);
- a lump in a breast; or
- liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue).
Other, less serious side effects may be more likely to occur. Continue to take esterified estrogens and talk to your doctor if you experience
- decreased appetite, nausea, or vomiting;
- swollen or tender breasts;
- acne or skin color changes;
- decreased sex drive;
- migraine headaches or dizziness;
- water retention (swollen hands, feet, or ankles);
- problems with wearing contact lenses;
- depression; or
- changes in your menstrual cycle or breakthrough bleeding.
Esterified estrogens increase the risk of developing a condition (endometrial hyperplasia) that may lead to cancer of the lining of the uterus. Taking progestins, another hormone drug, with esterified estrogens lowers the risk of developing this condition. Therefore, if your uterus has not been removed, your doctor may prescribe a progestin for you to take together with the estrogen. Visit your doctor regularly and report any unusual vaginal bleeding right away.
It is unclear to what extent estrogen treatments may affect the risk of breast cancer.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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