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Pronunciation: klor AM bue sil
Do not use chlorambucil if you are pregnant. It could harm the unborn baby.
Taking chlorambucil may increase your risk of developing other types of cancer. Chlorambucil may also affect fertility (your ability to have children), whether you are a man or a woman. Ask your doctor about your individual risk.
Chlorambucil can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection.
Do not receive a "live" vaccine while you are being treated with chlorambucil, and for at least 3 months after your treatment ends. The vaccine may not work as well during this time, and may not fully protect you from disease.
Stop taking chlorambucil and call your doctor at once if you have a seizure, red or peeling skin rash, severe nausea or stomach pain, jaundice (yellowing of your skin or eyes), fever, chills, sore throat, ongoing cough, flu symptoms, mouth sores, easy bruising or bleeding, or any unusual mass or lump.
Chlorambucil is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Chlorambucil is used to treat several types of cancer, including Hodgkin's disease and certain types of leukemia or lymphoma.
Chlorambucil may also be used for purposes not listed in this medication guide.
You should not use this medication if you are allergic to chlorambucil, or if you have received this medication in the past without successful treatment of your condition.
To make sure you can safely take chlorambucil, tell your doctor if you have any of these other conditions:
FDA pregnancy category D. Do not use chlorambucil if you are pregnant. It could harm the unborn baby. Use effective birth control, and tell your doctor if you become pregnant during treatment.
This medication may affect fertility (your ability to have children), whether you are a man or a woman.
It is not known whether chlorambucil passes into breast milk or if it could harm a nursing baby. You should not breast-feed while taking chlorambucil.
Taking chlorambucil may increase your risk of developing other types of cancer. Talk to your doctor about your specific risk.
You must remain under the care of a doctor while you are using chlorambucil.
Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Chlorambucil is usually taken for 3 to 6 weeks. Follow your doctor's instructions.
Your doctor may occasionally change your dose to make sure you get the best results.
Chlorambucil can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests. Visit your doctor regularly.
Store chlorambucil tablets in the refrigerator, do not freeze.
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include agitation, loss of balance or coordination, or seizure (convulsions).
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.
Do not receive a "live" vaccine while you are being treated with chlorambucil, and for at least 3 months after your treatment ends. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), oral polio, rotavirus, typhoid, varicella (chickenpox), H1N1 influenza, and nasal flu vaccine.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop taking chlorambucil and call your doctor at once if you have a serious side effect such as:
Less serious side effects:
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
There may be other drugs that can interact with chlorambucil. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Your doctor or pharmacist can provide more information about chlorambucil.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2013 Cerner Multum, Inc. Version: 4.03. Revision date: 11/29/2011.
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