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Study ID: UofM TALC

Observational Study of Swallowing Function After Treatment of Advanced Laryngeal Cancer


Traditionally cancer of the larynx and hypopharynx was treated by surgery alone (a total laryngectomy) which included removing the voice box, leaving the patient unable to speak naturally. With advances in treatment over the last couple of decades, chemotherapy and radiation therapy has become an alternative to surgery for many patients. Despite saving the voice box, chemoradiation has its own list of side effects that affects daily activities, such as eating. Patients agreeing to participate in this study are asked to complete a set of 4 questionnaires regarding swallowing function and overall well-being at 3 time points (baseline, and at 6 and 12 months post-surgery or 1st chemoradiation treatment). The type of treatment – chemoradiation or surgery - is determined by the treating physician and is not altered as a result of participation in this study.

Sioux Falls Region
Principal Investigator:
John Lee, MD


Active - Open to Accrual

For more information, call or email Bismarck Clinical Research at (701) 323-5760, Fargo and Bemidji Clinical Research at (701) 234-5890, or Sioux Falls Clinical Research at (605) 328-1368.

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