National Wilm's Tumor Study Late Effects
The objective of this study to determine the incidence of life-threatening medical conditions in survivors of Wilms tumor, specifically a) congestive heart failure; b) second malignant neoplasms (SMNs); c) renal failure; and d) pulmonary fibrosis and interstitial lung disease. Participants of this study have previously been treated for Wilms tumor. An additional objective is to relate the risks of these events to the type and amount of radiation and chemotherapy received and to determine mortality rates in former Wilms tumor patients and to compare these with age, calendar period, and sex-specific national population rates.
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