A Study Evaluating Limited Target Volume Boost Irradiation and Reduced Dose Craniospinal (18.00 Gy) and Chemotherapy in Children With Newly Diagnosed Standard Risk Medulloblastoma: A Phase III Double Randomized Trial
The purpose of this study is to find out if the overall dose of radiation to the brain and spine can be reduced without decreasing rates of survival in children with medulloblastoma. Children who participate in this trial have a cancer called medulloblastoma, which is a type of childhood brain tumor. Standard therapy for medulloblastoma includes surgery followed by radiation therapy (use of high-energy x-rays to kill cancer cells) to the brain and spinal cord with or without chemotherapy (treatment with anti-cancer drugs The study will also look at whether the volume of radiation given during the boost can be reduced without decreasing survival rates in children with medulloblastoma.
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