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Sioux Falls

Focus on Sioux Falls

The view from Sioux Falls is one of progress and promise. Named after the Big Sioux River that flows through the heart of the city, 150-thousand people call Sioux Falls home. Sanford Health in Sioux Falls is proud to serve an area that spans 74-thousand square miles.

Sanford USD Medical Center

  • Largest hospital in South Dakota
  • Largest employer in Sioux Falls
  • More than 4,500 employees
  • Primary teaching institution for the Sanford School of Medicine of the University of South Dakota
  • Top 100 Hospitals list

Look to the future

Travel our footprint with Sanford Medical Center Presidents Dr. Pat O'Brien and Dennis Millirons. They are highlighting the amazing things we're achieving and looking into the future—our blue horizons.


A closer look at Sioux Falls

Sioux Falls offers a variety of arts and culture, dining options, shopping, sports and other entertainment throughout the year, in both the historic downtown area as well as throughout the city. Sioux Falls boasts a well-developed park system and quality education, which is why it has been one of the top-rated areas for quality of life according to USA Today.

South Dakota has no state income tax and a low cost of living compared to other metro areas in the Midwest. Forbes Magazine ranked Sioux Falls the number one small city for business and careers four years in a row. The city offers one of the lowest unemployment rates in the nation.

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Sanford Health Sioux Falls region

  • 17 medical centers
  • 59 clinic locations
  • 74,382 square miles
  • Population: 897,865
  • Employees: 11,046
  • Physicians: 475
  • Advanced Practice Providers: 308
  • Licensed beds: 866